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Entity Details
Primary name
GAPD1_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q14C86
EntryName
GAPD1_HUMAN
FullName
GTPase-activating protein and VPS9 domain-containing protein 1
TaxID
9606
Evidence
evidence at protein level
Length
1478
SequenceStatus
complete
DateCreated
2008-03-18
DateModified
2021-06-02
Ontological Relatives
Genes
GAPVD1
GO terms
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GO
Name
GO:0005085
guanyl-nucleotide exchange factor activity
GO:0005096
GTPase activator activity
GO:0005768
endosome
GO:0005829
cytosol
GO:0005886
plasma membrane
GO:0006897
endocytosis
GO:0007165
signal transduction
GO:0032794
GTPase activating protein binding
GO:0043547
positive regulation of GTPase activity
GO:0045296
cadherin binding
GO:0051223
regulation of protein transport
GO:0061024
membrane organization
Subcellular Location
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Subcellular Location
Endosome
Membrane
Domains
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Domain
Name
Category
Type
IPR001936
Ras GTPase-activating domain
Domain
Domain
IPR003123
VPS9 domain
Domain
Domain
IPR008936
Rho GTPase activation protein
Family
Homologous superfamily
IPR037191
VPS9 domain superfamily
Family
Homologous superfamily
IPR041545
RABX5, catalytic core helical domain
Domain
Domain
Diseases
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Drugs
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Interactions
15 interactions
Interactor
Partner
Sources
Publications
Link
GAPD1_HUMAN
VAV2_HUMAN
BioGRID, IntAct
18654987
details
GAPD1_HUMAN
HSPB1_HUMAN
BioGRID, IntAct
25277244
details
GAPD1_HUMAN
SUMO2_HUMAN
BioGRID
32786267
details
GAPD1_HUMAN
1433B_HUMAN
BioGRID, HPRD, IntAct, MINT
15324660
17353931
24255178
26344197
28514442
details
GAPD1_HUMAN
1433Z_HUMAN
MINT
15161933
details
GAPD1_HUMAN
HSF1_HUMAN
BioGRID, IntAct
27173435
unassigned1312
details
GAPD1_HUMAN
TF3C4_HUMAN
BioGRID, IntAct
27173435
unassigned1312
details
GAPD1_HUMAN
EP15R_HUMAN
BioGRID, IntAct
27173435
unassigned1312
details
GAPD1_HUMAN
MCM6_HUMAN
BioGRID, IntAct
27173435
unassigned1312
details
GAPD1_HUMAN
MCM2_HUMAN
BioGRID, IntAct
27173435
unassigned1312
details
GAPD1_HUMAN
MCM4_HUMAN
BioGRID, IntAct
27173435
unassigned1312
details
GAPD1_HUMAN
JIP4_HUMAN
BioGRID, IntAct
27173435
unassigned1312
details
GAPD1_HUMAN
NS1BP_HUMAN
BioGRID, IntAct
27173435
unassigned1312
details
GAPD1_HUMAN
UBP15_HUMAN
BioGRID, IntAct
27173435
unassigned1312
details
GAPD1_HUMAN
CBL_HUMAN
BioGRID
17545148
details
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