Entity Details

Primary name GZMB
Entity type gene
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Details

PrimaryID3002
RefseqGeneNG_028340
SymbolGZMB
Namegranzyme B
Chromosome14
Location14q12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-17
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsGRAB_HUMAN

GO terms

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GOName
GO:0001772 immunological synapse
GO:0004252 serine-type endopeptidase activity
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0008236 serine-type peptidase activity
GO:0016020 membrane
GO:0017148 negative regulation of translation
GO:0019835 cytolysis
GO:0042267 natural killer cell mediated cytotoxicity
GO:0043231 intracellular membrane-bounded organelle
GO:0044194 cytolytic granule
GO:0051603 proteolysis involved in cellular protein catabolic process
GO:0070269 pyroptosis
GO:0140507 granzyme-mediated programmed cell death signaling pathway
GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Diseases

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