Entity Details

Primary name STING1
Entity type gene
Source Source Link

Details

PrimaryID340061
RefseqGeneNG_034249
SymbolSTING1
Namestimulator of interferon response cGAMP interactor 1
Chromosome5
Location5q31.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2003-03-28
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsSTING_HUMAN

GO terms

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GOName
GO:0000045 autophagosome assembly
GO:0000421 autophagosome membrane
GO:0002218 activation of innate immune response
GO:0002230 positive regulation of defense response to virus by host
GO:0005654 nucleoplasm
GO:0005741 mitochondrial outer membrane
GO:0005768 endosome
GO:0005776 autophagosome
GO:0005777 peroxisome
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0008134 transcription factor binding
GO:0016032 viral process
GO:0016239 positive regulation of macroautophagy
GO:0019901 protein kinase binding
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0030659 cytoplasmic vesicle membrane
GO:0030667 secretory granule membrane
GO:0031625 ubiquitin protein ligase binding
GO:0032092 positive regulation of protein binding
GO:0032479 regulation of type I interferon production
GO:0032481 positive regulation of type I interferon production
GO:0032728 positive regulation of interferon-beta production
GO:0035438 cyclic-di-GMP binding
GO:0035458 cellular response to interferon-beta
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043312 neutrophil degranulation
GO:0045087 innate immune response
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048471 perinuclear region of cytoplasm
GO:0050727 regulation of inflammatory response
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051259 protein complex oligomerization
GO:0051607 defense response to virus
GO:0061507 cyclic-GMP-AMP binding
GO:0061709 reticulophagy
GO:0071360 cellular response to exogenous dsRNA
GO:0071407 cellular response to organic cyclic compound
GO:1990701 integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane

Diseases

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Interactions

112 interactions

InteractorPartnerSourcesPublicationsLink
STING1IFI16BioGRID, InnateDB20890285 26121674 27764250 30193098 31665637 details
STING1STAT6IntAct22000020 details
STING1IRAK1BioGRID, IntAct21903422 details
STING1STT3ABioGRID, IntAct21903422 details
STING1DDOSTBioGRID, IntAct21903422 details
STING1SURF4BioGRID, IntAct21903422 29251827 details
STING1SGPL1BioGRID, IntAct21903422 details
STING1CCDC47BioGRID, IntAct21903422 details
STING1LTN1BioGRID, IntAct21903422 details
STING1MBOAT7BioGRID, IntAct21903422 details
STING1ZNF16UniProt21874239 details
STING1STING1BioGRID, DIP, HPIDb, IntAct19433799 21074459 22312431 22728658 22728659 22728660 23542348 30018345 30405246 30842659 33086059 details
STING1CMTM5BioGRID, IntAct32296183 details
STING1PLLPBioGRID, IntAct32296183 details
STING1TECRBioGRID, IntAct32296183 details
STING1REEP6BioGRID, IntAct32296183 details
STING1TMEM100BioGRID, IntAct32296183 details
STING1YIPF2BioGRID, IntAct32296183 details
STING1SMIM1BioGRID, IntAct32296183 details
STING1STX5BioGRID, IntAct32296183 details
STING1LEPROTL1BioGRID, IntAct32296183 details
STING1SSR2DIP18724357 details
STING1TRIM32BioGRID22745133 details
STING1RNF26BioGRID25254379 details
STING1USP20BioGRID27801882 30814308 details
STING1USP49BioGRID27801882 30943264 details
STING1MUL1BioGRID28763789 details
STING1MYSM1BioGRID33086059 details
STING1RNF115BioGRID33139700 details
STING1MAVSBioGRID, DIP, HPIDb, IntAct18724357 19416887 20080758 22000020 22312431 22908223 22911572 23542348 24622840 details
STING1TBK1BioGRID, DIP, HPIDb, IntAct18724357 19416887 19433799 21074459 21903422 22745133 23542348 24622840 28346439 28763789 29899553 30943264 31534043 32383759 33086059 33139700 details
STING1DDX58BioGRID, DIP, IntAct18724357 22312431 details
STING1IFIT2DIP19416887 details
STING1IFIT1DIP19416887 details
STING1IKBKEBioGRID, DIP19433799 22312431 28346439 details
STING1IRF3BioGRID, IntAct24622840 25636800 30018345 33086059 details
STING1UBBIntAct24622840 details
STING1TRIM56BioGRID21074459 details
STING1RNF5BioGRID19285439 details
STING1TSPAN6BioGRID22908223 details
STING1TOMM70BioGRID20628368 details
STING1TRAF3BioGRID24622840 27716849 details
STING1USP18BioGRID27801882 details
STING1USP2BioGRID27801882 details
STING1USP3BioGRID27801882 details
STING1USP13BioGRID27801882 details
STING1USP22BioGRID27801882 details
STING1USP35BioGRID27801882 details
STING1USP50BioGRID27801882 details
STING1PAN2BioGRID27801882 details
STING1CD40BioGRID27716849 details
STING1TRAF2BioGRID27716849 details
STING1FAF2BioGRID29899553 details
STING1TP53BioGRID30193098 details
STING1TRAF6BioGRID30193098 details
STING1MAP3K14BioGRID30018345 details
STING1CYLDBioGRID30388174 details
STING1H2BC21BioGRID27764250 details
STING1CGASBioGRID27764250 details
STING1MARCHF1BioGRID32606244 details
STING1OTUD5BioGRID32879469 details
STING1YIPF5BioGRID, IntAct21903422 details
STING1NPC1BioGRID, IntAct21903422 details
STING1HM13BioGRID, IntAct21903422 details
STING1ABCC1BioGRID, IntAct21903422 details
STING1ACSL3BioGRID, IntAct21903422 details
STING1STT3BBioGRID, IntAct21903422 details
STING1CNNM3BioGRID, IntAct21903422 details
STING1CLPTM1LBioGRID, IntAct21903422 details
STING1GLMNBioGRID, IntAct21903422 details
STING1TMEM259BioGRID, IntAct21903422 details
STING1SLC39A14BioGRID, IntAct21903422 details
STING1SEC61A1BioGRID, IntAct21903422 details
STING1ACSL4HPIDb22911572 details
STING1NECTIN4BioGRID, IntAct28514442 details
STING1SEC61BBioGRID, DIP18724357 34079125 details
STING1MYO6IntAct29251827 details
STING1SAE1IntAct29251827 details
STING1INTS7IntAct29251827 details
STING1EXOSC5IntAct29251827 details
STING1PRKD2IntAct29251827 details
STING1INTS4IntAct29251827 details
STING1MITD1IntAct29251827 details
STING1DDX54IntAct29251827 details
STING1INTS1IntAct29251827 details
STING1RBM45IntAct29251827 details
STING1RAPH1IntAct29251827 details
STING1GRIPAP1IntAct29251827 details
STING1SKP1IntAct29251827 details
STING1EIF2B2IntAct29251827 details
STING1SSR1IntAct29251827 details
STING1DNMT1IntAct29251827 details
STING1PTPN1IntAct29251827 details
STING1AGPAT2IntAct29251827 details
STING1PRCCIntAct29251827 details
STING1VAC14IntAct29251827 details
STING1INTS2IntAct29251827 details
STING1ZNF780BIntAct29251827 details
STING1AUP1IntAct29251827 details
STING1STAT3IntAct29251827 details
STING1HRGIntAct29251827 details
STING1IL1BIntAct29251827 details
STING1SLC16A7IntAct29251827 details
STING1ZSWIM8IntAct29251827 details
STING1TPRIntAct29251827 details
STING1RHBDD1BioGRID31177093 details
STING1OTULINLBioGRID31056421 details
STING1RPN1BioGRID32788342 34079125 details
STING1DERL1BioGRID34079125 details
STING1HSD17B11BioGRID34079125 details
STING1HSD3B7BioGRID34079125 details
STING1METTL7ABioGRID34079125 details