Entity Details

Primary name FADS1
Entity type gene
Source Source Link

Details

PrimaryID3992
RefseqGene
SymbolFADS1
Namefatty acid desaturase 1
Chromosome11
Location11q12.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-01-18
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsFADS1_HUMAN

GO terms

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GOName
GO:0000248 C-5 sterol desaturase activity
GO:0005739 mitochondrion
GO:0005789 endoplasmic reticulum membrane
GO:0006355 regulation of transcription, DNA-templated
GO:0006636 unsaturated fatty acid biosynthetic process
GO:0007267 cell-cell signaling
GO:0008654 phospholipid biosynthetic process
GO:0009267 cellular response to starvation
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016213 linoleoyl-CoA desaturase activity
GO:0016491 oxidoreductase activity
GO:0019222 regulation of metabolic process
GO:0036109 alpha-linolenic acid metabolic process
GO:0042759 long-chain fatty acid biosynthetic process
GO:0043231 intracellular membrane-bounded organelle
GO:0043651 linoleic acid metabolic process
GO:0045595 regulation of cell differentiation
GO:0046456 icosanoid biosynthetic process
GO:0062076 acyl-CoA delta5-desaturase activity

Diseases

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Interactions

26 interactions

InteractorPartnerSourcesPublicationsLink
FADS1XRN1BioGRID15231747 details
FADS1PAAF1BioGRID, IntAct17353931 details
FADS1DHCR7BioGRID, IntAct17353931 details
FADS1CCDC22BioGRID, IntAct26496610 details
FADS1GPR21BioGRID, IntAct28514442 details
FADS1HTR2CBioGRID, IntAct28514442 details
FADS1TMCO3BioGRID, IntAct28514442 details
FADS1GABREBioGRID, IntAct26186194 28514442 details
FADS1SLC39A12BioGRID, IntAct28514442 details
FADS1SLC18A1BioGRID, IntAct28514442 details
FADS1TACR1BioGRID, IntAct28514442 details
FADS1GRPRBioGRID, IntAct28514442 details
FADS1IL17RCBioGRID, IntAct28514442 details
FADS1PTH1RBioGRID, IntAct26186194 28514442 details
FADS1SIRT2BioGRID, IntAct26186194 28514442 details
FADS1RNF181BioGRID, IntAct28514442 details
FADS1UQCC1BioGRID, IntAct28514442 details
FADS1ASPSCR1BioGRID, IntAct28514442 details
FADS1VMP1BioGRID, IntAct30833792 details
FADS1PSEN1BioGRID, UniProt25959826 details
FADS1RNF4BioGRID29180619 details
FADS1H4C1BioGRID30804502 details
FADS1LMBR1LBioGRID31073040 details
FADS1PLEKHA4BioGRID31091453 details
FADS1FAM20CBioGRID32149426 details
FADS1TRIM25BioGRID29117863 details