Entity Details

Primary name MMP12
Entity type gene
Source Source Link

Details

PrimaryID4321
RefseqGeneNG_032936
SymbolMMP12
Namematrix metallopeptidase 12
Chromosome11
Location11q22.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-20
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsMMP12_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001046 core promoter sequence-specific DNA binding
GO:0004175 endopeptidase activity
GO:0004222 metalloendopeptidase activity
GO:0005509 calcium ion binding
GO:0005518 collagen binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006508 proteolysis
GO:0006606 protein import into nucleus
GO:0008270 zinc ion binding
GO:0022617 extracellular matrix disassembly
GO:0030198 extracellular matrix organization
GO:0030574 collagen catabolic process
GO:0031012 extracellular matrix
GO:0032727 positive regulation of interferon-alpha production
GO:0035313 wound healing, spreading of epidermal cells
GO:0043565 sequence-specific DNA binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048286 lung alveolus development
GO:0050691 regulation of defense response to virus by host
GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing
GO:0060309 elastin catabolic process
GO:0060339 negative regulation of type I interferon-mediated signaling pathway
GO:0060340 positive regulation of type I interferon-mediated signaling pathway
GO:0060435 bronchiole development
GO:0098586 cellular response to virus
GO:1904645 response to amyloid-beta
GO:1904905 negative regulation of endothelial cell-matrix adhesion via fibronectin

Diseases

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Interactions

6 interactions