Entity Details

Primary name ADIPO_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15848
EntryNameADIPO_HUMAN
FullNameAdiponectin
TaxID9606
Evidenceevidence at protein level
Length244
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesADIPOQ

GO terms

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GOName
GO:0001666 response to hypoxia
GO:0001934 positive regulation of protein phosphorylation
GO:0005102 signaling receptor binding
GO:0005125 cytokine activity
GO:0005179 hormone activity
GO:0005576 extracellular region
GO:0005581 collagen trimer
GO:0005615 extracellular space
GO:0005783 endoplasmic reticulum
GO:0006006 glucose metabolic process
GO:0006091 generation of precursor metabolites and energy
GO:0006635 fatty acid beta-oxidation
GO:0007584 response to nutrient
GO:0007623 circadian rhythm
GO:0009617 response to bacterium
GO:0009744 response to sucrose
GO:0009749 response to glucose
GO:0009967 positive regulation of signal transduction
GO:0009986 cell surface
GO:0010467 gene expression
GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway
GO:0010739 positive regulation of protein kinase A signaling
GO:0010745 negative regulation of macrophage derived foam cell differentiation
GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0010875 positive regulation of cholesterol efflux
GO:0010906 regulation of glucose metabolic process
GO:0014823 response to activity
GO:0019395 fatty acid oxidation
GO:0030336 negative regulation of cell migration
GO:0030853 negative regulation of granulocyte differentiation
GO:0031953 negative regulation of protein autophosphorylation
GO:0032720 negative regulation of tumor necrosis factor production
GO:0032757 positive regulation of interleukin-8 production
GO:0032869 cellular response to insulin stimulus
GO:0033034 positive regulation of myeloid cell apoptotic process
GO:0033691 sialic acid binding
GO:0034115 negative regulation of heterotypic cell-cell adhesion
GO:0034383 low-density lipoprotein particle clearance
GO:0034612 response to tumor necrosis factor
GO:0035690 cellular response to drug
GO:0042304 regulation of fatty acid biosynthetic process
GO:0042593 glucose homeostasis
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043407 negative regulation of MAP kinase activity
GO:0045471 response to ethanol
GO:0045599 negative regulation of fat cell differentiation
GO:0045650 negative regulation of macrophage differentiation
GO:0045721 negative regulation of gluconeogenesis
GO:0045776 negative regulation of blood pressure
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045923 positive regulation of fatty acid metabolic process
GO:0046326 positive regulation of glucose import
GO:0046888 negative regulation of hormone secretion
GO:0050728 negative regulation of inflammatory response
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050765 negative regulation of phagocytosis
GO:0050805 negative regulation of synaptic transmission
GO:0050873 brown fat cell differentiation
GO:0051384 response to glucocorticoid
GO:0062023 collagen-containing extracellular matrix
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0070543 response to linoleic acid
GO:0070994 detection of oxidative stress
GO:0071320 cellular response to cAMP
GO:0071639 positive regulation of monocyte chemotactic protein-1 production
GO:0071872 cellular response to epinephrine stimulus
GO:0072659 protein localization to plasma membrane
GO:0090317 negative regulation of intracellular protein transport
GO:0110113 positive regulation of lipid transporter activity
GO:0120162 positive regulation of cold-induced thermogenesis
GO:0120163 negative regulation of cold-induced thermogenesis
GO:1900121 negative regulation of receptor binding
GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation
GO:1904753 negative regulation of vascular associated smooth muscle cell migration
GO:1905598 negative regulation of low-density lipoprotein receptor activity
GO:2000279 negative regulation of DNA biosynthetic process
GO:2000467 positive regulation of glycogen (starch) synthase activity
GO:2000478 positive regulation of metanephric glomerular visceral epithelial cell development
GO:2000481 positive regulation of cAMP-dependent protein kinase activity
GO:2000534 positive regulation of renal albumin absorption
GO:2000584 negative regulation of platelet-derived growth factor receptor-alpha signaling pathway
GO:2000590 negative regulation of metanephric mesenchymal cell migration

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001073 C1q domainDomainDomain
IPR008160 Collagen triple helix repeatRepeatRepeat
IPR008983 Tumour necrosis factor-like domain superfamilyFamilyHomologous superfamily
IPR028572 AdiponectinFamilyFamily

Diseases

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Interactions

66 interactions

InteractorPartnerSourcesPublicationsLink
ADIPO_HUMANSGTA_HUMANBioGRID, IntAct25416956 25910212 31515488 32296183 details
ADIPO_HUMANKELL_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANTNF14_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANBIK_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANCAMLG_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANB2L13_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANNEMP1_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANFAS_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANMS4A3_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANMFSD6_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANAQP6_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANCYBC1_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANCPLX4_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANPEX12_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANCNR2_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANT179B_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANPVR_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANAMGO1_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANGPR42_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANFKBP7_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANFCGR1_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANSYAP1_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANSIG12_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANBTNL9_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANF209A_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANGP152_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANCOQ9_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANS35E3_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANFNDC9_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANCLD9_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANS35C2_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANDHB11_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANTRI35_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANMRM1_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANMFF_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANSYNE4_HUMANBioGRID, IntAct25416956 25910212 32296183 details
ADIPO_HUMANTMPS2_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANCLC2D_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANASGR2_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANCR3L1_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANCLC10_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANPKR2_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANSGTB_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANTM237_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANCC107_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANERP29_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANMF14B_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANNACHO_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANSCN3B_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANKCNK5_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANINGR2_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANBSND_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANMUC1_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANCD79A_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANS22AN_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANMO2R1_HUMANBioGRID, IntAct32296183 details
ADIPO_HUMANBNI3L_HUMANBioGRID, IntAct25910212 details
ADIPO_HUMANKASH5_HUMANBioGRID, IntAct25416956 25910212 details
ADIPO_HUMANHD_HUMANIntAct32814053 details
ADIPO_HUMANADIPO_HUMANBioGRID12021245 19855092 details
ADIPO_HUMANMOT8_HUMANBioGRID32296183 details
ADIPO_HUMANC1T9A_HUMANIntAct19666007 details
ADIPO_HUMANC1T9B_HUMANIntAct19666007 details
ADIPO_HUMANPDGFB_HUMANBioGRID12070119 details
ADIPO_HUMANCAD13_HUMANHPRD15210937 details
ADIPO_HUMANPAQR2_HUMANHPRD12802337 details