Entity Details

Primary name ORC2
Entity type gene
Source Source Link

Details

PrimaryID4999
RefseqGene
SymbolORC2
Nameorigin recognition complex subunit 2
Chromosome2
Location2q33.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1997-06-24
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsORC2_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000781 chromosome, telomeric region
GO:0000792 heterochromatin
GO:0000808 origin recognition complex
GO:0000939 inner kinetochore
GO:0003688 DNA replication origin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005664 nuclear origin of replication recognition complex
GO:0005813 centrosome
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0016020 membrane
GO:0036388 pre-replicative complex assembly

Diseases

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Interactions

96 interactions

InteractorPartnerSourcesPublicationsLink
ORC2MCM2BioGRID, HPRD, IntAct12614612 15232106 details
ORC2MCM10BioGRID, HPRD, IntAct, UniProt11095689 15232106 details
ORC2ORC1BioGRID, DIP, HPRD, IntAct11323433 11779870 11931757 12614612 15232106 16549788 17716973 20850016 22398447 26496610 31160578 details
ORC2CDC5LBioGRID, HPRD, IntAct, MINT15232106 20467437 details
ORC2CDC6BioGRID, HPRD, IntAct11046155 12614612 15232106 details
ORC2ORC5BioGRID, DIP, HPRD, IntAct11323433 11395502 12004060 12614612 15232106 16549788 17716973 20850016 22939629 26264872 26496610 31160578 9765232 details
ORC2ORC4BioGRID, DIP, HPRD, IntAct11323433 11395502 12004060 12614612 15232106 15910003 16549788 17716973 20850016 31160578 31467278 9353276 details
ORC2CDK2BioGRID, HPRD, IntAct11931757 15232106 details
ORC2CDT1BioGRID, HPRD, IntAct15232106 details
ORC2MCM3BioGRID, HPRD, IntAct11046155 12364596 12614612 details
ORC2MCM4BioGRID, HPRD, IntAct12364596 12614612 details
ORC2TERF2BioGRID, MINT16799465 18761675 details
ORC2EP300BioGRID, MINT20808282 details
ORC2ORC3BioGRID, DIP, HPRD, IntAct10402192 11323433 11395502 12004060 12614612 15910003 16549788 17525332 17716973 20850016 22939629 26344197 26496610 31160578 details
ORC2RAD18BioGRID, IntAct22681887 32296183 details
ORC2CTNNA3BioGRID, IntAct32296183 details
ORC2RIPPLY3BioGRID, IntAct32296183 details
ORC2ORC6BioGRID, DIP, HPRD, IntAct11323433 12004060 12614612 15910003 16549788 26186194 28514442 details
ORC2MCM7BioGRID, HPRD12614612 details
ORC2RPA1BioGRID, HPRD12614612 details
ORC2RPA2BioGRID, HPRD12614612 details
ORC2DBF4BioGRID, HPRD12441400 12614612 details
ORC2CDC45BioGRID, HPRD12614612 9660782 details
ORC2ORC2BioGRID12614612 31160578 details
ORC2MCM5BioGRID, HPRD12614612 26344197 details
ORC2MCM6BioGRID, HPRD12614612 details
ORC2KAT7BioGRID16428461 details
ORC2H3-4BioGRID20850016 details
ORC2H4-16BioGRID20850016 details
ORC2CCNA2BioGRID, IntAct11931757 31160578 details
ORC2TERF1MINT16799465 details
ORC2TERF2IPMINT16799465 details
ORC2RNF8IntAct18001825 details
ORC2HMGA1BioGRID, DIP, MINT18234858 18946490 details
ORC2LRWD1BioGRID, IntAct20850016 22935713 22939629 26344197 26496610 31160578 details
ORC2XRCC5BioGRID, HPRD12393188 15910003 details
ORC2BRCA1BioGRID17525332 25184681 details
ORC2MCM8BioGRID15684404 details
ORC2CCL2BioGRID21383955 details
ORC2CBX5BioGRID21383955 details
ORC2XRCC6BioGRID15910003 30585729 31160578 details
ORC2OBI1BioGRID31160578 details
ORC2CCNA1IntAct11931757 details
ORC2SNW1BioGRID, MINT20467437 details
ORC2APEX1MINT20808282 details
ORC2ILF2BioGRID, MINT20808282 details
ORC2FOXM1BioGRID, MINT25609649 details
ORC2FOXE1BioGRID, MINT25609649 details
ORC2FOXG1BioGRID, MINT25609649 details
ORC2FOXL1BioGRID, MINT25609649 details
ORC2FOXQ1BioGRID, MINT25609649 details
ORC2FOXS1BioGRID, MINT25609649 details
ORC2TEAD2BioGRID, MINT25609649 details
ORC2KIF11BioGRID, IntAct26496610 details
ORC2PARD6ABioGRID, IntAct26496610 details
ORC2BRINP1BioGRID, IntAct26496610 details
ORC2RBM8ABioGRID, IntAct26496610 details
ORC2STN1BioGRID, IntAct26186194 28514442 details
ORC2SIRT2BioGRID, IntAct26186194 28514442 details
ORC2RPGRBioGRID, IntAct28514442 details
ORC2ANGMINT28777577 details
ORC2H3C1BioGRID, IntAct29568061 details
ORC2H3C4IntAct29568061 details
ORC2H3C3IntAct29568061 details
ORC2H3C6IntAct29568061 details
ORC2H3C11IntAct29568061 details
ORC2H3C8IntAct29568061 details
ORC2H3C12IntAct29568061 details
ORC2H3C10IntAct29568061 details
ORC2H3C2IntAct29568061 details
ORC2H3C7IntAct29568061 details
ORC2NUCKS1BioGRID22939629 details
ORC2LMNABioGRID22412018 details
ORC2FXR1BioGRID24778252 31160578 details
ORC2CDC42BPBBioGRID26344197 details
ORC2RABGAP1BioGRID26344197 details
ORC2PES1BioGRID26344197 details
ORC2NFATC1BioGRID25609649 details
ORC2RNF4BioGRID29180619 details
ORC2ESR2BioGRID29509190 details
ORC2RUNX1BioGRID28533407 details
ORC2EZH2BioGRID27634302 details
ORC2RECQL4BioGRID29229926 details
ORC2ACTC1BioGRID30890647 details
ORC2NR2C2BioGRID30463901 details
ORC2H4C1BioGRID30804502 details
ORC2PLEKHA4BioGRID31091453 details
ORC2NSD2BioGRID31248990 details
ORC2CITBioGRID31586073 details
ORC2KIF14BioGRID31586073 details
ORC2PRC1BioGRID31586073 details
ORC2CICBioGRID29844126 details
ORC2CBX3BioGRID34079125 details
ORC2H2BC8BioGRID34079125 details
ORC2ZNF330BioGRID34079125 details
ORC2HNRNPH1BioGRID26760575 details