Entity Details

Primary name TLR8
Entity type gene
Source Source Link

Details

PrimaryID51311
RefseqGeneNG_012882
SymbolTLR8
Nametoll like receptor 8
ChromosomeX
LocationXp22.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-04-27
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsTLR8_HUMAN

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0001932 regulation of protein phosphorylation
GO:0002224 toll-like receptor signaling pathway
GO:0002755 MyD88-dependent toll-like receptor signaling pathway
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0003725 double-stranded RNA binding
GO:0003727 single-stranded RNA binding
GO:0004888 transmembrane signaling receptor activity
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0009615 response to virus
GO:0009897 external side of plasma membrane
GO:0010008 endosome membrane
GO:0016021 integral component of membrane
GO:0016064 immunoglobulin mediated immune response
GO:0032695 negative regulation of interleukin-12 production
GO:0032727 positive regulation of interferon-alpha production
GO:0032728 positive regulation of interferon-beta production
GO:0032729 positive regulation of interferon-gamma production
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032755 positive regulation of interleukin-6 production
GO:0032757 positive regulation of interleukin-8 production
GO:0034158 toll-like receptor 8 signaling pathway
GO:0036020 endolysosome membrane
GO:0038023 signaling receptor activity
GO:0038187 pattern recognition receptor activity
GO:0042802 identical protein binding
GO:0045087 innate immune response
GO:0045089 positive regulation of innate immune response
GO:0051607 defense response to virus
GO:0071260 cellular response to mechanical stimulus

Diseases

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