Entity Details

Primary name B2M
Entity type gene
Source Source Link

Details

PrimaryID567
RefseqGeneNG_012920
SymbolB2M
Namebeta-2-microglobulin
Chromosome15
Location15q21.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsB2MG_HUMAN

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0001895 retina homeostasis
GO:0001916 positive regulation of T cell mediated cytotoxicity
GO:0002237 response to molecule of bacterial origin
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
GO:0002481 antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
GO:0002726 positive regulation of T cell cytokine production
GO:0003254 regulation of membrane depolarization
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005788 endoplasmic reticulum lumen
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0006826 iron ion transport
GO:0007611 learning or memory
GO:0009897 external side of plasma membrane
GO:0010977 negative regulation of neuron projection development
GO:0012507 ER to Golgi transport vesicle membrane
GO:0016020 membrane
GO:0019731 antibacterial humoral response
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I
GO:0030670 phagocytic vesicle membrane
GO:0031901 early endosome membrane
GO:0031905 early endosome lumen
GO:0032092 positive regulation of protein binding
GO:0033077 T cell differentiation in thymus
GO:0034756 regulation of iron ion transport
GO:0035580 specific granule lumen
GO:0042026 protein refolding
GO:0042493 response to drug
GO:0042612 MHC class I protein complex
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0042824 MHC class I peptide loading complex
GO:0043312 neutrophil degranulation
GO:0045087 innate immune response
GO:0045646 regulation of erythrocyte differentiation
GO:0046686 response to cadmium ion
GO:0048260 positive regulation of receptor-mediated endocytosis
GO:0050680 negative regulation of epithelial cell proliferation
GO:0050690 regulation of defense response to virus by virus
GO:0050768 negative regulation of neurogenesis
GO:0050776 regulation of immune response
GO:0050829 defense response to Gram-negative bacterium
GO:0050830 defense response to Gram-positive bacterium
GO:0051289 protein homotetramerization
GO:0052031 modulation by symbiont of host defense response
GO:0055038 recycling endosome membrane
GO:0055072 iron ion homeostasis
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
GO:0070062 extracellular exosome
GO:0071222 cellular response to lipopolysaccharide
GO:0071281 cellular response to iron ion
GO:0071283 cellular response to iron(III) ion
GO:0071316 cellular response to nicotine
GO:0090647 modulation of age-related behavioral decline
GO:1900121 negative regulation of receptor binding
GO:1900122 positive regulation of receptor binding
GO:1904434 positive regulation of ferrous iron binding
GO:1904437 positive regulation of transferrin receptor binding
GO:1904724 tertiary granule lumen
GO:1990000 amyloid fibril formation
GO:1990712 HFE-transferrin receptor complex
GO:2000774 positive regulation of cellular senescence
GO:2000978 negative regulation of forebrain neuron differentiation

Diseases

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Interactions

72 interactions

InteractorPartnerSourcesPublicationsLink
B2MCD1BBioGRID, HPRD, IntAct, MINT12118248 14764708 26186194 28514442 details
B2MHLA-CBioGRID, HPRD, IntAct, MINT10429675 2450918 26186194 27649529 28514442 28546555 details
B2MFCGRTBioGRID, HPRD, IntAct, MINT10933786 12006623 28514442 31289263 details
B2MHLA-BBioGRID, HPRD, IntAct, MINT10975842 11738047 11823531 12244049 17057332 2450918 26186194 27649529 28514442 8624811 8624812 details
B2MHLA-ABioGRID, HPRD, IntAct, MINT11502003 1448153 20831383 20844028 24163410 26439010 27649529 8805302 93026 details
B2MBAG6BioGRID, HPRD, IntAct16169070 details
B2MPRSS23BioGRID, HPRD, IntAct16169070 details
B2MCD1AHPRD, IntAct12833155 15723809 details
B2MGRB2BioGRID, IntAct18624398 details
B2MB2MBioGRID, DIP, HPRD, MINT12023961 17108084 18543331 18579777 19172750 19564620 20826442 21131979 21220305 21569201 22289140 22575645 23645685 details
B2MPCOLCEmatrixdb24117177 details
B2MPCNAIntAct, UniProt23527218 26030842 details
B2MHSPB2bhf-ucl, BioGRID26465331 details
B2MCD1DBioGRID, DIP, HPRD10221650 11257307 17581592 details
B2MMR1DIP23051753 details
B2MCHRM4BioGRID, MINT28298427 details
B2MTP63IntAct12692135 details
B2MPYGO1IntAct32814053 details
B2MA2MBioGRID, HPRD10731476 details
B2MCRYABBioGRID23645685 details
B2MCXCR4BioGRID18083706 details
B2MHFEBioGRID, DIP, HPRD, MINT, UniProt10638746 10791995 15965644 20618438 details
B2MCALRBioGRID, HPRD, IntAct25241761 8769474 details
B2MCD244IntAct20164429 details
B2MHLA-FBioGRID, HPRD, IntAct11169396 20483783 26186194 27649529 details
B2MLILRB1HPRD, IntAct12897781 27649529 details
B2MCD1EBioGRID, HPRD, IntAct10948205 28514442 details
B2MHLA-GDIP, HPRD, IntAct17056715 18332182 9228302 details
B2MHLA-EBioGRID, HPRD, IntAct10064069 18332182 9605335 details
B2MTAPBPBioGRID17055437 details
B2MTAP2BioGRID8805302 details
B2MCD8AHPRD11914379 details
B2MTAP1BioGRID, HPIDb, IntAct17055437 18802093 details
B2MLIN37IntAct17531812 details
B2MLIN54IntAct17531812 details
B2MMAPK15BioGRID, IntAct23602568 details
B2MMAP1SBioGRID, IntAct24366813 details
B2MERBB3BioGRID, IntAct24189400 details
B2MKPNA2IntAct24018270 details
B2MINSIntAct24018270 details
B2MEBI3IntAct24018270 details
B2MNCR2IntAct20164429 details
B2MKIR3DL1IntAct27649529 details
B2MKIR3DS1IntAct27649529 details
B2MKIR2DS1IntAct28546555 details
B2MRANGRFBioGRID, IntAct28514442 details
B2MNUSAP1BioGRID, IntAct28514442 details
B2MRGPD6IntAct28514442 details
B2MRGPD5BioGRID, IntAct28514442 details
B2MCDCA2BioGRID, IntAct28514442 details
B2MRGPD2BioGRID, IntAct28514442 details
B2MDLGAP5BioGRID, IntAct28514442 details
B2MKPNB1BioGRID, IntAct28514442 details
B2MPPATBioGRID, IntAct28514442 details
B2MUBE2IBioGRID, IntAct28514442 details
B2MRANBP2BioGRID, IntAct28514442 details
B2MRANGAP1BioGRID, IntAct28514442 details
B2MTPST1BioGRID, IntAct28514442 details
B2MNEMP1BioGRID, IntAct28514442 details
B2MKPNA4BioGRID, IntAct28514442 details
B2MKPNA3BioGRID, IntAct28514442 details
B2MTFRCDIP10638746 20133674 details
B2MOTOFBioGRID, IntAct30021884 details
B2MHMCN1BioGRID, IntAct30021884 details
B2MOSBPBioGRID, IntAct30021884 details
B2MMORC2BioGRID, IntAct30021884 details
B2MKLRD1IntAct18332182 details
B2MKLRC1IntAct18332182 details
B2MCFTRBioGRID26618866 details
B2MSAMHD1BioGRID30833792 details
B2MCD274BioGRID32941674 details
B2MTRIM37BioGRID33194618 details