Entity Details

Primary name RSPO1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ2MKA7
EntryNameRSPO1_HUMAN
FullNameR-spondin-1
TaxID9606
Evidenceevidence at protein level
Length263
SequenceStatuscomplete
DateCreated2006-05-16
DateModified2021-06-02

Ontological Relatives

GenesRSPO1

GO terms

Show/Hide Table
GOName
GO:0001664 G protein-coupled receptor binding
GO:0001934 positive regulation of protein phosphorylation
GO:0002090 regulation of receptor internalization
GO:0005102 signaling receptor binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0008201 heparin binding
GO:0016055 Wnt signaling pathway
GO:0030177 positive regulation of Wnt signaling pathway
GO:0090263 positive regulation of canonical Wnt signaling pathway

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus
Secreted

Domains

Show/Hide Table
DomainNameCategoryType
IPR000884 Thrombospondin type-1 (TSP1) repeatRepeatRepeat
IPR006212 Furin-like repeatRepeatRepeat
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR036383 Thrombospondin type-1 (TSP1) repeat superfamilyFamilyHomologous superfamily
IPR042991 R-spondin-1FamilyFamily
IPR043601 R-spondin, Fu-CRD domainDomainDomain

Diseases

Show/Hide Table