Entity Details

Primary name CCL21
Entity type gene
Source Source Link

Details

PrimaryID6366
RefseqGene
SymbolCCL21
NameC-C motif chemokine ligand 21
Chromosome9
Location9p13.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-06-24
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsCCL21_HUMAN

GO terms

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GOName
GO:0001768 establishment of T cell polarity
GO:0001771 immunological synapse formation
GO:0001954 positive regulation of cell-matrix adhesion
GO:0002407 dendritic cell chemotaxis
GO:0002548 monocyte chemotaxis
GO:0002606 positive regulation of dendritic cell antigen processing and presentation
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007267 cell-cell signaling
GO:0008009 chemokine activity
GO:0010560 positive regulation of glycoprotein biosynthetic process
GO:0010820 positive regulation of T cell chemotaxis
GO:0030593 neutrophil chemotaxis
GO:0030838 positive regulation of actin filament polymerization
GO:0031274 positive regulation of pseudopodium assembly
GO:0031295 T cell costimulation
GO:0031529 ruffle organization
GO:0031640 killing of cells of other organism
GO:0031732 CCR7 chemokine receptor binding
GO:0033630 positive regulation of cell adhesion mediated by integrin
GO:0034695 response to prostaglandin E
GO:0035759 mesangial cell-matrix adhesion
GO:0038116 chemokine (C-C motif) ligand 21 signaling pathway
GO:0042379 chemokine receptor binding
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043547 positive regulation of GTPase activity
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity
GO:0045860 positive regulation of protein kinase activity
GO:0046330 positive regulation of JNK cascade
GO:0048020 CCR chemokine receptor binding
GO:0048245 eosinophil chemotaxis
GO:0048247 lymphocyte chemotaxis
GO:0048260 positive regulation of receptor-mediated endocytosis
GO:0048469 cell maturation
GO:0050921 positive regulation of chemotaxis
GO:0051209 release of sequestered calcium ion into cytosol
GO:0051491 positive regulation of filopodium assembly
GO:0051897 positive regulation of protein kinase B signaling
GO:0060326 cell chemotaxis
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
GO:0070098 chemokine-mediated signaling pathway
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071346 cellular response to interferon-gamma
GO:0071347 cellular response to interleukin-1
GO:0071356 cellular response to tumor necrosis factor
GO:0090023 positive regulation of neutrophil chemotaxis
GO:0090630 activation of GTPase activity
GO:0097026 dendritic cell dendrite assembly
GO:1903237 negative regulation of leukocyte tethering or rolling
GO:1990869 cellular response to chemokine
GO:2000147 positive regulation of cell motility
GO:2000406 positive regulation of T cell migration
GO:2000529 positive regulation of myeloid dendritic cell chemotaxis
GO:2000548 negative regulation of dendritic cell dendrite assembly
GO:2000669 negative regulation of dendritic cell apoptotic process

Diseases

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Interactions

45 interactions

InteractorPartnerSourcesPublicationsLink
CCL21UBQLN4BioGRID, HPRD, IntAct16713569 details
CCL21GOT2BioGRID, MINT21900206 details
CCL21LRRK1BioGRID, IntAct24947832 29513927 details
CCL21LRRK2IntAct24947832 details
CCL21C3orf52BioGRID, IntAct32296183 details
CCL21OTPBioGRID, IntAct32296183 details
CCL21TMEM107BioGRID, IntAct32296183 details
CCL21CCL5bhf-ucl, BioGRID28381538 details
CCL21PF4bhf-ucl, BioGRID28381538 details
CCL21CXCL12bhf-ucl, BioGRID28381538 details
CCL21CCL17bhf-ucl, BioGRID28381538 details
CCL21CCL13bhf-ucl, BioGRID28381538 details
CCL21CXCL9bhf-ucl, BioGRID28381538 details
CCL21PPBPbhf-ucl, BioGRID28381538 details
CCL21XCL1bhf-ucl, BioGRID28381538 details
CCL21CCL28bhf-ucl, BioGRID28381538 details
CCL21CCL26bhf-ucl, BioGRID28381538 details
CCL21CCL23bhf-ucl, BioGRID28381538 details
CCL21PF4V1bhf-ucl, BioGRID28381538 details
CCL21CCL24bhf-ucl, BioGRID28381538 details
CCL21CXCL14bhf-ucl, BioGRID28381538 details
CCL21CXCL10bhf-ucl, BioGRID28381538 details
CCL21CXCL2bhf-ucl, BioGRID28381538 details
CCL21XCL2bhf-ucl, BioGRID28381538 details
CCL21CXCL11bhf-ucl, BioGRID28381538 details
CCL21CXCL17bhf-ucl, BioGRID28381538 details
CCL21JPH3IntAct32814053 details
CCL21VCANBioGRID, HPRD11083865 details
CCL21ACKR4BioGRID, HPRD10706668 details
CCL21CCR7HPRD, Molecular Connections21172016 9507024 9585422 details
CCL21IGFBP7HPRD12847218 details
CCL21ACKR2HPRD10706668 details
CCL21CTSDHPRD12651610 details
CCL21CXCL13HPRD15546958 details
CCL21KLHL26BioGRID, IntAct28514442 details
CCL21KLHL22BioGRID, IntAct28514442 details
CCL21TRIP6BioGRID, IntAct28514442 details
CCL21CLTCL1BioGRID, IntAct28514442 details
CCL21SMARCB1BioGRID, IntAct30021884 details
CCL21HNRNPA2B1BioGRID, IntAct30021884 details
CCL21IRF5IntAct33179750 details
CCL21EGR1IntAct33179750 details
CCL21SMAD4IntAct33179750 details
CCL21WT1IntAct33179750 details
CCL21TCF4IntAct33179750 details