Entity Details

Primary name STK3
Entity type gene
Source Source Link

Details

PrimaryID6788
RefseqGene
SymbolSTK3
Nameserine/threonine kinase 3
Chromosome8
Location8q22.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-24
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSTK3_HUMAN

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0001841 neural tube formation
GO:0003157 endocardium development
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006468 protein phosphorylation
GO:0006915 apoptotic process
GO:0007165 signal transduction
GO:0007417 central nervous system development
GO:0008285 negative regulation of cell population proliferation
GO:0031098 stress-activated protein kinase signaling cascade
GO:0032092 positive regulation of protein binding
GO:0032147 activation of protein kinase activity
GO:0032991 protein-containing complex
GO:0035329 hippo signaling
GO:0035556 intracellular signal transduction
GO:0042802 identical protein binding
GO:0043065 positive regulation of apoptotic process
GO:0043539 protein serine/threonine kinase activator activity
GO:0045600 positive regulation of fat cell differentiation
GO:0046330 positive regulation of JNK cascade
GO:0046621 negative regulation of organ growth
GO:0050821 protein stabilization
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051897 positive regulation of protein kinase B signaling
GO:0060215 primitive hemopoiesis
GO:0060706 cell differentiation involved in embryonic placenta development
GO:0060800 regulation of cell differentiation involved in embryonic placenta development
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0097284 hepatocyte apoptotic process
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors

Diseases

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Interactions

121 interactions

InteractorPartnerSourcesPublicationsLink
STK3RASSF5BioGRID, DIP, IntAct, MINT, Molecular Connections16892067 20562859 20920251 21988832 23455922 23972470 24255178 24366813 24981860 details
STK3SAV1BioGRID, HPRD, IntAct, MINT, Molecular Connections15688006 16930133 17379520 20562859 20920251 21988832 23455922 24255178 24366813 24981860 26186194 28514442 32296183 details
STK3RASSF1BioGRID, IntAct, MINT, Molecular Connections14729613 17379520 17598981 17889669 18347058 20086174 20920251 23455922 24255178 24366813 24981860 26186194 28205554 28514442 32296183 details
STK3RASSF2BioGRID, IntAct, MINT, Molecular Connections20562859 20920251 23455922 24255178 24366813 24981860 25416956 26186194 28514442 31515488 32296183 details
STK3RASSF3BioGRID, IntAct, Molecular Connections20920251 23455922 24255178 24366813 details
STK3RASSF4BioGRID, IntAct, Molecular Connections20920251 23455922 24255178 24366813 25416956 32296183 details
STK3RASSF6BioGRID, IntAct, Molecular Connections19797269 20920251 24366813 26186194 28514442 details
STK3STK4BioGRID, IntAct, MINT, Molecular Connections20562859 20920251 23386615 23455922 24255178 24366813 24981860 26344197 28205554 details
STK3GABARAPBioGRID, IntAct20562859 31857374 details
STK3GABARAPL1BioGRID, IntAct20562859 31857374 details
STK3GABARAPL2IntAct20562859 details
STK3MAP1LC3BBioGRID, IntAct20562859 31006538 31857374 details
STK3MAP1LC3CBioGRID, IntAct20562859 31857374 details
STK3STK3BioGRID, DIP, HPRD, IntAct12554736 15618521 18082144 20086174 20562859 23972470 28205554 details
STK3PLK1BioGRID, IntAct20562859 24255178 27566175 details
STK3ORM2BioGRID, IntAct21988832 details
STK3PEX19BioGRID, IntAct21988832 details
STK3CPNE1BioGRID, IntAct21988832 details
STK3HSPE1BioGRID, IntAct21988832 details
STK3SULT2A1BioGRID, IntAct21988832 details
STK3ZC3H7ABioGRID, IntAct21988832 details
STK3DDAH2BioGRID, MINT21900206 details
STK3GBP2BioGRID, MINT21900206 details
STK3KHSRPBioGRID, MINT21900206 details
STK3MPP1BioGRID, MINT21900206 details
STK3PHAXBioGRID, MINT21900206 details
STK3QARS1BioGRID, MINT21900206 details
STK3SLMAPBioGRID, IntAct24255178 25416956 details
STK3MOB1ABioGRID, DIP, IntAct18362890 23972470 24255178 31941533 details
STK3MOB1BBioGRID, IntAct19919647 24255178 32296183 details
STK3MOB4BioGRID, IntAct19797269 24255178 details
STK3TFPTBioGRID, IntAct25416956 32296183 details
STK3TRAF1BioGRID, IntAct25416956 32296183 details
STK3FAM9BBioGRID, IntAct25416956 details
STK3GAD1BioGRID, IntAct25416956 details
STK3PLEKHF2IntAct32296183 details
STK3MOB3BBioGRID, IntAct32296183 details
STK3SNIP1BioGRID, IntAct32296183 details
STK3RAF1BioGRID, DIP, HPRD15618521 17889669 20086174 20212043 24929361 details
STK3JPH3IntAct32814053 details
STK3LATS1BioGRID15688006 17379520 19962312 22195963 details
STK3MBPBioGRID20212043 details
STK3LATS2BioGRID, HPRD15688006 19919647 24255178 26898830 details
STK3LRRK2BioGRID20949042 details
STK3EIF4EBP1BioGRID20090955 details
STK3AKT1BioGRID20086174 20231902 details
STK3GMCL1BioGRID25416956 details
STK3CDK1BioGRID27566175 details
STK3KEAP1BioGRID30765703 details
STK3MARK2BioGRID31080060 details
STK3OGTBioGRID32994395 details
STK3CASP3BioGRID, HPRD, IntAct11278283 25241761 details
STK3ZDHHC17IntAct24705354 details
STK3PRDX1IntAct23386615 details
STK3KIF3BBioGRID, IntAct27173435 unassigned1312 details
STK3CNKSR1BioGRID, HPRD15075335 details
STK3NRDCBioGRID18362890 details
STK3PTPN14BioGRID22948661 27432908 details
STK3TAFAZZINBioGRID22078877 details
STK3CTTNBP2NLBioGRID24255178 details
STK3FBXW11BioGRID25332235 25900982 details
STK3MAP1LC3ABioGRID, IntAct20562859 details
STK3ATG4BBioGRID, IntAct20562859 details
STK3CACYBPBioGRID, IntAct20562859 details
STK3SQSTM1IntAct20562859 details
STK3WWTR1IntAct22078877 details
STK3TPTEP2-CSNK1EIntAct23455922 details
STK3CSNK1EBioGRID, IntAct23455922 details
STK3MAP1BBioGRID, IntAct23455922 24366813 details
STK3MAP1SBioGRID, IntAct23455922 24255178 24366813 details
STK3DSTBioGRID, IntAct23455922 details
STK3VAPABioGRID, IntAct23455922 28514442 details
STK3CDK3BioGRID, IntAct23455922 details
STK3NEBBioGRID, IntAct23455922 details
STK3ACACABioGRID, IntAct23455922 details
STK3MRPL40BioGRID, IntAct24366813 details
STK3RUNDC3BBioGRID, IntAct24255178 details
STK3KIF2CBioGRID, IntAct24255178 details
STK3TSPYL1BioGRID, IntAct24255178 details
STK3RAE1BioGRID, IntAct24255178 details
STK3AURKBBioGRID, IntAct24255178 details
STK3THAP12BioGRID, IntAct24255178 details
STK3YWHABBioGRID, IntAct24255178 details
STK3ERLIN2BioGRID, IntAct24255178 details
STK3STRN4BioGRID, IntAct24255178 details
STK3STRNBioGRID, IntAct24255178 details
STK3STRIP1BioGRID, IntAct24255178 details
STK3STRN3BioGRID, IntAct24255178 details
STK3FGFR1OP2BioGRID, IntAct24255178 details
STK3EGLN3BioGRID, IntAct26972000 details
STK3CFAP298BioGRID, IntAct26496610 details
STK3CENPOBioGRID, IntAct26496610 details
STK3CEP128BioGRID, IntAct26638075 details
STK3CEP43BioGRID, IntAct26638075 details
STK3HSCBBioGRID, IntAct28380382 details
STK3VAPBBioGRID, IntAct28514442 details
STK3BTRCBioGRID, IntAct25900982 28514442 details
STK3SKP2BioGRID, IntAct28514442 details
STK3KIF2BBioGRID, IntAct28514442 details
STK3ZNF133BioGRID, IntAct28514442 details
STK3ZNF695BioGRID, IntAct28514442 details
STK3ZIM2BioGRID, IntAct28514442 details
STK3ADCYAP1BioGRID, IntAct26186194 28514442 details
STK3ZNF420BioGRID, IntAct28514442 details
STK3GLYR1BioGRID, MINT24981860 details
STK3CENPVBioGRID, MINT24981860 details
STK3NOP16BioGRID, MINT24981860 details
STK3FREM1BioGRID20562859 details
STK3NSUN5BioGRID26344197 details
STK3IFI16BioGRID25693804 details
STK3XPO1BioGRID26673895 details
STK3MTMR7BioGRID27432908 details
STK3RECQL4BioGRID29229926 details
STK3FBXW7BioGRID29346117 details
STK3VCPBioGRID29540532 details
STK3PLEKHA4BioGRID31091453 details
STK3KIF14BioGRID31586073 details
STK3BCAR1BioGRID33001583 details
STK3NR4A1BioGRID33087562 details
STK3GOLGA1BioGRID34079125 details
STK3VIRMABioGRID29507755 details