Entity Details

Primary name SYN2
Entity type gene
Source Source Link

Details

PrimaryID6854
RefseqGeneNG_011728
SymbolSYN2
Namesynapsin II
Chromosome3
Location3p25.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1995-08-25
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSYN2_HUMAN

GO terms

Show/Hide Table
GOName
GO:0005524 ATP binding
GO:0005886 plasma membrane
GO:0007268 chemical synaptic transmission
GO:0007269 neurotransmitter secretion
GO:0014069 postsynaptic density
GO:0017156 calcium-ion regulated exocytosis
GO:0030672 synaptic vesicle membrane
GO:0031201 SNARE complex
GO:0042802 identical protein binding
GO:0045202 synapse
GO:0097091 synaptic vesicle clustering
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098978 glutamatergic synapse

Diseases

Show/Hide Table
Disease IDSourceNameDescription
181500 OMIMSchizophrenia (SCZD)A complex, multifactorial psychotic disorder or group of disorders characterized by disturbances in the form and content of thought (e.g. delusions, hallucinations), in mood (e.g. inappropriate affect), in sense of self and relationship to the external world (e.g. loss of ego boundaries, withdrawal), and in behavior (e.g bizarre or apparently purposeless behavior). Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. Some patients manifest schizophrenic as well as bipolar disorder symptoms and are often given the diagnosis of schizoaffective disorder. Disease susceptibility may be associated with variants affecting the gene represented in this entry.

Interactions

17 interactions