Entity Details

Primary name TLR1
Entity type gene
Source Source Link

Details

PrimaryID7096
RefseqGeneNG_016228
SymbolTLR1
Nametoll like receptor 1
Chromosome4
Location4p14
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-12-15
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsTLR1_HUMAN

GO terms

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GOName
GO:0001774 microglial cell activation
GO:0001775 cell activation
GO:0002224 toll-like receptor signaling pathway
GO:0002755 MyD88-dependent toll-like receptor signaling pathway
GO:0004888 transmembrane signaling receptor activity
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007165 signal transduction
GO:0016020 membrane
GO:0030670 phagocytic vesicle membrane
GO:0032755 positive regulation of interleukin-6 production
GO:0032757 positive regulation of interleukin-8 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0034130 toll-like receptor 1 signaling pathway
GO:0034137 positive regulation of toll-like receptor 2 signaling pathway
GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex
GO:0035663 Toll-like receptor 2 binding
GO:0038023 signaling receptor activity
GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway
GO:0042116 macrophage activation
GO:0042495 detection of triacyl bacterial lipopeptide
GO:0042802 identical protein binding
GO:0045087 innate immune response
GO:0045121 membrane raft
GO:0050135 NAD(P)+ nucleosidase activity
GO:0061809 NAD+ nucleotidase, cyclic ADP-ribose generating
GO:0071221 cellular response to bacterial lipopeptide
GO:0071723 lipopeptide binding
GO:0071727 cellular response to triacyl bacterial lipopeptide

Diseases

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