Entity Details

Primary name TMPRSS2
Entity type gene
Source Source Link

Details

PrimaryID7113
RefseqGeneNG_047085
SymbolTMPRSS2
Nametransmembrane serine protease 2
Chromosome21
Location21q22.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-24
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsTMPS2_HUMAN

GO terms

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GOName
GO:0004252 serine-type endopeptidase activity
GO:0005044 scavenger receptor activity
GO:0005576 extracellular region
GO:0005654 nucleoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006508 proteolysis
GO:0008236 serine-type peptidase activity
GO:0016540 protein autoprocessing
GO:0046598 positive regulation of viral entry into host cell
GO:0070062 extracellular exosome

Diseases

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Interactions

78 interactions

InteractorPartnerSourcesPublicationsLink
TMPRSS2VKORC1IntAct32296183 details
TMPRSS2VAMP5BioGRID, IntAct32296183 details
TMPRSS2MFSD6IntAct32296183 details
TMPRSS2FAM3CBioGRID, IntAct32296183 details
TMPRSS2SLC38A7IntAct32296183 details
TMPRSS2SLC35A1BioGRID, IntAct32296183 details
TMPRSS2ZFPL1BioGRID, IntAct32296183 details
TMPRSS2TNFBioGRID, IntAct32296183 details
TMPRSS2C1QL4BioGRID, IntAct32296183 details
TMPRSS2TMEM86ABioGRID, IntAct32296183 details
TMPRSS2TMEM222BioGRID, IntAct32296183 details
TMPRSS2TMEM229BBioGRID, IntAct32296183 details
TMPRSS2PLP1BioGRID, IntAct32296183 details
TMPRSS2EDDM3BBioGRID, IntAct32296183 details
TMPRSS2SCDBioGRID, IntAct32296183 details
TMPRSS2CXCL9BioGRID, IntAct32296183 details
TMPRSS2C3orf52BioGRID, IntAct32296183 details
TMPRSS2CFHR5BioGRID, IntAct32296183 details
TMPRSS2AQP1BioGRID, IntAct32296183 details
TMPRSS2FAXDC2BioGRID, IntAct32296183 details
TMPRSS2STX7BioGRID, IntAct32296183 details
TMPRSS2STX8BioGRID, IntAct32296183 details
TMPRSS2PLP2BioGRID, IntAct32296183 details
TMPRSS2PGAP2BioGRID, IntAct32296183 details
TMPRSS2SMIM1BioGRID, IntAct32296183 details
TMPRSS2BNIP3BioGRID, IntAct32296183 details
TMPRSS2CMTM7BioGRID, IntAct32296183 details
TMPRSS2SFTPCBioGRID, IntAct32296183 details
TMPRSS2TMEM243BioGRID, IntAct32296183 details
TMPRSS2CTXN3BioGRID, IntAct32296183 details
TMPRSS2TMEM120BBioGRID, IntAct32296183 details
TMPRSS2ANKRD46BioGRID, IntAct32296183 details
TMPRSS2MOSPD3BioGRID, IntAct32296183 details
TMPRSS2CLEC7ABioGRID, IntAct32296183 details
TMPRSS2TMEM128BioGRID, IntAct32296183 details
TMPRSS2TMEM79BioGRID, IntAct32296183 details
TMPRSS2PTCH1BioGRID, IntAct32296183 details
TMPRSS2CNIH2BioGRID, IntAct32296183 details
TMPRSS2CLN6BioGRID, IntAct32296183 details
TMPRSS2IGFBP5BioGRID, IntAct32296183 details
TMPRSS2ADIPOQBioGRID, IntAct32296183 details
TMPRSS2UPK2BioGRID, IntAct32296183 details
TMPRSS2BRICD5BioGRID, IntAct32296183 details
TMPRSS2TMEM11BioGRID, IntAct32296183 details
TMPRSS2CNIH3BioGRID, IntAct32296183 details
TMPRSS2PLNBioGRID, IntAct32296183 details
TMPRSS2DEFB103ABioGRID, IntAct32296183 details
TMPRSS2DEFB103BBioGRID, IntAct32296183 details
TMPRSS2SEC22ABioGRID, IntAct32296183 details
TMPRSS2BNIP2BioGRID, IntAct32296183 details
TMPRSS2BMP10BioGRID, IntAct32296183 details
TMPRSS2TMEM86BBioGRID, IntAct32296183 details
TMPRSS2NINJ2BioGRID, IntAct32296183 details
TMPRSS2ERG28BioGRID, IntAct32296183 details
TMPRSS2PLLPBioGRID, IntAct32296183 details
TMPRSS2PTTG1IPBioGRID, IntAct32296183 details
TMPRSS2TMEM218BioGRID, IntAct32296183 details
TMPRSS2C2CD2LBioGRID, IntAct32296183 details
TMPRSS2TMEM60BioGRID, IntAct32296183 details
TMPRSS2CYBC1BioGRID, IntAct32296183 details
TMPRSS2SELENOKBioGRID, IntAct32296183 details
TMPRSS2ACE2BioGRID, UniProt21068237 details
TMPRSS2CLK1BioGRID26167880 details
TMPRSS2TMPRSS2HPRD11245484 details
TMPRSS2DCAF4BioGRID30945288 details
TMPRSS2ARIntAct19345326 20478527 20541699 23260764 23518348 26175416 27728805 details
TMPRSS2ERGIntAct20478527 21575865 details
TMPRSS2CREBBPIntAct20541699 details
TMPRSS2PRKDCIntAct21575865 26175416 details
TMPRSS2PARP1IntAct21575865 details
TMPRSS2XRCC5IntAct21575865 details
TMPRSS2XRCC6IntAct21575865 details
TMPRSS2SIAH2IntAct23518348 details
TMPRSS2EP300IntAct26175416 details
TMPRSS2POLR2AIntAct26175416 details
TMPRSS2MYCNIntAct27728805 details
TMPRSS2EZH2IntAct27728805 details
TMPRSS2HNRNPLBioGRID28611215 details