Entity Details

Primary name MED25
Entity type gene
Source Source Link

Details

PrimaryID81857
RefseqGeneNG_017091
SymbolMED25
Namemediator complex subunit 25
Chromosome19
Location19q13.33
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-05-27
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsMED25_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001223 transcription coactivator binding
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0008134 transcription factor binding
GO:0016592 mediator complex
GO:0035563 positive regulation of chromatin binding
GO:0042974 retinoic acid receptor binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046965 retinoid X receptor binding
GO:0048147 negative regulation of fibroblast proliferation
GO:0060260 regulation of transcription initiation from RNA polymerase II promoter
GO:2001178 positive regulation of mediator complex assembly

Diseases

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Interactions

72 interactions

InteractorPartnerSourcesPublicationsLink
MED25RARABioGRID, HPRD, MINT17641689 details
MED25THRBMINT17641689 details
MED25RXRABioGRID, HPRD, MINT17641689 details
MED25NR3C1BioGRID, MINT17641689 details
MED25ABL1MINT19290556 details
MED25LCKMINT19290556 details
MED25CYSRT1BioGRID, IntAct32296183 details
MED25TFGBioGRID, IntAct32296183 details
MED25ESRP1BioGRID, IntAct32296183 details
MED25FAM168BBioGRID, IntAct32296183 details
MED25LASP1BioGRID, IntAct32296183 details
MED25PEF1BioGRID, IntAct32296183 details
MED25NCKIPSDBioGRID, IntAct32296183 details
MED25TLE5BioGRID, IntAct32296183 details
MED25PLEKHB2BioGRID, IntAct32296183 details
MED25STAT5BBioGRID, IntAct32296183 details
MED25KRTAP6-1BioGRID, IntAct32296183 details
MED25USP54BioGRID, IntAct32296183 details
MED25KLHL12BioGRID, IntAct32296183 details
MED25HGSBioGRID, IntAct32296183 details
MED25WWP2BioGRID, IntAct32296183 details
MED25ODAMBioGRID, IntAct32296183 details
MED25WWOXBioGRID, IntAct32296183 details
MED25EYA2BioGRID, IntAct32296183 details
MED25SERTAD3BioGRID, IntAct32296183 details
MED25OXER1BioGRID, IntAct32296183 details
MED25RUSC1BioGRID, IntAct32296183 details
MED25ESR1BioGRID, IntAct17641689 24960263 31527615 details
MED25SREBF1BioGRID11834832 16799563 details
MED25THRABioGRID17641689 details
MED25CREBBPBioGRID, HPRD17641689 details
MED25CTDP1BioGRID16239144 details
MED25MED19BioGRID, IntAct14576168 15175163 21729782 23563140 26186194 28514442 details
MED25MED10BioGRID, IntAct14576168 15175163 15989967 24882805 details
MED25MED26BioGRID, IntAct14657022 15175163 21729782 details
MED25MED15BioGRID, HPRD, IntAct14657022 14983011 24882805 details
MED25MED14BioGRID, IntAct14657022 24882805 25792360 details
MED25MED16BioGRID, IntAct14657022 24882805 25792360 details
MED25MED24BioGRID, IntAct24882805 25792360 26344197 details
MED25MED23BioGRID, IntAct, MINT14657022 24882805 25281560 25792360 26344197 details
MED25MED12BioGRID, IntAct14657022 20133760 26496610 details
MED25CDK8BioGRID, DIP, HPRD, IntAct14638676 14657022 14983011 20098423 25792360 26186194 26496610 28514442 29568061 details
MED25MED1BioGRID, DIP, HPRD, IntAct14657022 14983011 15989967 17641689 20098423 20133760 25792360 28514442 details
MED25MED6BioGRID, HPRD, IntAct14657022 14983011 17641689 25792360 details
MED25MED28BioGRID15175163 20133760 details
MED25TRRAPBioGRID18418385 details
MED25ZC3H13BioGRID20133760 details
MED25TRIP4BioGRID20133760 details
MED25STN1BioGRID20133760 details
MED25QKIBioGRID20133760 details
MED25MED13BioGRID14657022 29568061 details
MED25MED25BioGRID14657022 details
MED25MED17BioGRID14657022 details
MED25MED7BioGRID14657022 details
MED25HCFC1HPRD14983011 details
MED25MED8HPRD14638676 details
MED25MED9BioGRID, HPRD, IntAct14638676 15175163 details
MED25MED29BioGRID, IntAct15175163 details
MED25POLR2FBioGRID, IntAct26496610 details
MED25NOTCH1BioGRID, MINT23022380 details
MED25TP53BP1BioGRID, UniProt29656893 details
MED25MED4BioGRID, MINT25281560 details
MED25TADA2ABioGRID20508642 details
MED25EPAS1BioGRID23275444 details
MED25MED18BioGRID28514442 details
MED25MED21BioGRID28514442 details
MED25CCNCBioGRID28514442 details
MED25FEZ1BioGRID28514442 details
MED25ESR2BioGRID29509190 details
MED25SMAD1BioGRID27703004 details
MED25SMAD2BioGRID27703004 details
MED25BRD4BioGRID32416067 details