Entity Details

Primary name SFRP5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ5T4F7
EntryNameSFRP5_HUMAN
FullNameSecreted frizzled-related protein 5
TaxID9606
Evidenceevidence at transcript level
Length317
SequenceStatuscomplete
DateCreated2005-03-15
DateModified2021-06-02

Ontological Relatives

GenesSFRP5

GO terms

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GOName
GO:0005615 extracellular space
GO:0006915 apoptotic process
GO:0007163 establishment or maintenance of cell polarity
GO:0007165 signal transduction
GO:0007275 multicellular organism development
GO:0007601 visual perception
GO:0008285 negative regulation of cell population proliferation
GO:0009653 anatomical structure morphogenesis
GO:0017147 Wnt-protein binding
GO:0030154 cell differentiation
GO:0030178 negative regulation of Wnt signaling pathway
GO:0030510 regulation of BMP signaling pathway
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0051898 negative regulation of protein kinase B signaling
GO:0060070 canonical Wnt signaling pathway
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:2000057 negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001134 Netrin domainDomainDomain
IPR008993 Tissue inhibitor of metalloproteinases-like, OB-foldFamilyHomologous superfamily
IPR015526 Frizzled/secreted frizzled-related proteinFamilyFamily
IPR018933 Netrin module, non-TIMP typeDomainDomain
IPR020067 Frizzled domainDomainDomain
IPR034860 Secreted frizzled-related protein 5FamilyFamily
IPR036790 Frizzled cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR041761 SFRP5, cysteine-rich domainDomainDomain

Diseases

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Interactions

4 interactions