Entity Details

Primary name TMC8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IU68
EntryNameTMC8_HUMAN
FullNameTransmembrane channel-like protein 8
TaxID9606
Evidenceevidence at protein level
Length726
SequenceStatuscomplete
DateCreated2005-12-06
DateModified2021-06-02

Ontological Relatives

GenesTMC8

GO terms

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GOName
GO:0001558 regulation of cell growth
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005887 integral component of plasma membrane
GO:0008381 mechanosensitive ion channel activity
GO:0031333 negative regulation of protein-containing complex assembly
GO:0031965 nuclear membrane
GO:0032091 negative regulation of protein binding
GO:0043120 tumor necrosis factor binding
GO:0055069 zinc ion homeostasis
GO:0070062 extracellular exosome
GO:0140311 protein sequestering activity
GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR012496 TMC domainDomainDomain
IPR038900 Transmembrane channel-like proteinFamilyFamily

Diseases

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Interactions

4 interactions