Entity Details

Primary name EXOC8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IYI6
EntryNameEXOC8_HUMAN
FullNameExocyst complex component 8
TaxID9606
Evidenceevidence at protein level
Length725
SequenceStatuscomplete
DateCreated2006-03-21
DateModified2021-06-02

Ontological Relatives

GenesEXOC8

GO terms

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GOName
GO:0000145 exocyst
GO:0005770 late endosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006887 exocytosis
GO:0006893 Golgi to plasma membrane transport
GO:0007032 endosome organization
GO:0008104 protein localization
GO:0015031 protein transport
GO:0016020 membrane
GO:0016241 regulation of macroautophagy
GO:0022617 extracellular matrix disassembly
GO:0030426 growth cone
GO:0031252 cell leading edge
GO:0031267 small GTPase binding
GO:0034613 cellular protein localization
GO:0035091 phosphatidylinositol binding
GO:0048471 perinuclear region of cytoplasm
GO:0060271 cilium assembly

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR016159 Cullin repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR032403 Exocyst component Exo84, C-terminalDomainDomain
IPR033961 Exocyst complex component Exo84FamilyFamily
IPR042560 Exocyst component Exo84, C-terminal, subdomain 2FamilyHomologous superfamily
IPR042561 Exocyst component Exo84, C-terminal, subdomain 1FamilyHomologous superfamily

Diseases

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Interactions

102 interactions

InteractorPartnerSourcesPublicationsLink
EXOC8_HUMANUSBP1_HUMANBioGRID, HPRD, IntAct16189514 32296183 details
EXOC8_HUMANK1C20_HUMANBioGRID, HPRD, IntAct16189514 details
EXOC8_HUMANTAD2A_HUMANBioGRID, HPRD, IntAct16189514 details
EXOC8_HUMANK1C15_HUMANBioGRID, HPRD, IntAct16189514 details
EXOC8_HUMANHGS_HUMANBioGRID, HPRD, IntAct16189514 details
EXOC8_HUMANBL1S6_HUMANBioGRID, HPRD, IntAct16189514 32296183 details
EXOC8_HUMANK1C19_HUMANBioGRID, HPRD, IntAct16189514 32296183 details
EXOC8_HUMANK1C18_HUMANBioGRID, HPRD, IntAct16189514 details
EXOC8_HUMANPCM1_HUMANBioGRID, HPRD, IntAct16189514 32296183 details
EXOC8_HUMANCC85B_HUMANBioGRID, HPRD, IntAct16189514 details
EXOC8_HUMANR3GEF_HUMANBioGRID, IntAct19060904 details
EXOC8_HUMANMBIP1_HUMANBioGRID, IntAct19060904 25416956 details
EXOC8_HUMANEFHC2_HUMANBioGRID, IntAct19060904 details
EXOC8_HUMANWASH1_HUMANBioGRID, IntAct24344185 32296183 details
EXOC8_HUMANK1H1_HUMANBioGRID, IntAct25416956 details
EXOC8_HUMANCE57L_HUMANBioGRID, IntAct25416956 details
EXOC8_HUMANIKZF3_HUMANBioGRID, IntAct25416956 31515488 32296183 details
EXOC8_HUMANRALB_HUMANBioGRID, IntAct14525976 21241894 24056301 26387716 27173435 28514442 unassigned1312 details
EXOC8_HUMANTRI27_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANTFP11_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANLZTS1_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANCAN3_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANT2EB_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANCCHCR_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANVP37B_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANGOGA2_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANITF2_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANNAB2_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANGO45_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANHTF4_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANAIMP2_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANRO52_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANBICRL_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANMARH7_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANKRT36_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANTB22B_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANZN628_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANSCAR5_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANELL2_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANUQCC2_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANZN566_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANF217B_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANRUSC1_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANSTMN3_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANSNPC1_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANDMAP1_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANZSCA4_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANBL1S2_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANISY1_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANSYT17_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANTRI54_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANBORC6_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANIHO1_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANSKT_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANPRR35_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANKIFC3_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANSYCE1_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANK22O_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANNDC80_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANMIPO1_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANUBP54_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANTRI14_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANKRT34_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANMTUS2_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANRINT1_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANATP23_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANGRAM4_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANNUP54_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANZC21A_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANAN36B_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANPBX4_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANBEX2_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANMB3L1_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANC19L2_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANMYOZ3_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANZNF35_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANESS2_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANZN177_HUMANBioGRID, IntAct32296183 details
EXOC8_HUMANRAB43_HUMANIntAct32296183 details
EXOC8_HUMANEXOC2_HUMANBioGRID, HPRD, IntAct14525976 22939629 24056301 26344197 27173435 28514442 unassigned1312 details
EXOC8_HUMANRALA_HUMANBioGRID, HPRD11406615 14525976 details
EXOC8_HUMANLNX1_HUMANBioGRID22889411 details
EXOC8_HUMANULK1_HUMANBioGRID21241894 details
EXOC8_HUMANSASH1_HUMANBioGRID30480076 details
EXOC8_HUMANRPGF3_HUMANBioGRID32296183 details
EXOC8_HUMANCCD33_HUMANBioGRID32296183 details
EXOC8_HUMANCDSN_HUMANBioGRID32296183 details
EXOC8_HUMANVPS16_HUMANBioGRID32296183 details
EXOC8_HUMANBECN1_HUMANBioGRID, IntAct21241894 26387716 details
EXOC8_HUMANEXOC4_HUMANBioGRID, IntAct21241894 22939629 26344197 27173435 28514442 unassigned1312 details
EXOC8_HUMANSRC8_HUMANIntAct24344185 details
EXOC8_HUMANEGFR_HUMANBioGRID, IntAct23956138 25594178 details
EXOC8_HUMANEXOC5_HUMANBioGRID, IntAct22939629 26344197 27173435 28514442 unassigned1312 details
EXOC8_HUMANEXOC6_HUMANBioGRID, IntAct26344197 27173435 28514442 unassigned1312 details
EXOC8_HUMANEXC6B_HUMANBioGRID, IntAct26344197 27173435 28514442 unassigned1312 details
EXOC8_HUMANEXOC7_HUMANBioGRID, IntAct26344197 27173435 28514442 unassigned1312 details
EXOC8_HUMANEXOC1_HUMANBioGRID, IntAct27173435 28514442 unassigned1312 details
EXOC8_HUMANRAB8A_HUMANBioGRID, IntAct27173435 unassigned1312 details
EXOC8_HUMANEXOC3_HUMANBioGRID, IntAct22939629 26344197 27173435 28514442 unassigned1312 details
EXOC8_HUMANRUBIC_HUMANBioGRID21241894 details
EXOC8_HUMANBAKOR_HUMANBioGRID21241894 details
EXOC8_HUMANPK3C3_HUMANBioGRID21241894 details