Entity Details

Primary name ZSWM2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NEG5
EntryNameZSWM2_HUMAN
FullNameE3 ubiquitin-protein ligase ZSWIM2
TaxID9606
Evidenceevidence at protein level
Length633
SequenceStatuscomplete
DateCreated2004-01-16
DateModified2021-06-02

Ontological Relatives

GenesZSWIM2

GO terms

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GOName
GO:0000209 protein polyubiquitination
GO:0006915 apoptotic process
GO:0008270 zinc ion binding
GO:0043621 protein self-association
GO:0061630 ubiquitin protein ligase activity
GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000433 Zinc finger, ZZ-typeDomainDomain
IPR001841 Zinc finger, RING-typeDomainDomain
IPR007527 Zinc finger, SWIM-typeDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR039903 E3 ubiquitin-protein ligase Zswim2FamilyFamily
IPR043145 Zinc finger, ZZ-type superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ZSWM2_HUMANMAGAB_HUMANBioGRID, HPRD, IntAct16189514 details
ZSWM2_HUMANUBE2U_HUMANBioGRID, IntAct19690564 details