Entity Details

Primary name ARHGA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15013
EntryNameARHGA_HUMAN
FullNameRho guanine nucleotide exchange factor 10
TaxID9606
Evidenceevidence at protein level
Length1369
SequenceStatuscomplete
DateCreated2004-07-05
DateModified2021-06-02

Ontological Relatives

GenesARHGEF10

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005813 centrosome
GO:0005829 cytosol
GO:0019894 kinesin binding
GO:0022011 myelination in peripheral nervous system
GO:0030036 actin cytoskeleton organization
GO:0035023 regulation of Rho protein signal transduction
GO:0051298 centrosome duplication
GO:0051496 positive regulation of stress fiber assembly
GO:0090307 mitotic spindle assembly
GO:0090630 activation of GTPase activity

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000219 Dbl homology (DH) domainDomainDomain
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR030632 Rho guanine nucleotide exchange factor 10FamilyFamily
IPR035899 Dbl homology (DH) domain superfamilyFamilyHomologous superfamily
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily
IPR039919 Rho guanine nucleotide exchange factor 10/17FamilyFamily

Diseases

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