Entity Details

Primary name RSPO3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BXY4
EntryNameRSPO3_HUMAN
FullNameR-spondin-3
TaxID9606
Evidenceevidence at protein level
Length272
SequenceStatuscomplete
DateCreated2006-05-16
DateModified2021-06-02

Ontological Relatives

GenesRSPO3

GO terms

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GOName
GO:0001974 blood vessel remodeling
GO:0002040 sprouting angiogenesis
GO:0005102 signaling receptor binding
GO:0005109 frizzled binding
GO:0005576 extracellular region
GO:0008201 heparin binding
GO:0016055 Wnt signaling pathway
GO:0030111 regulation of Wnt signaling pathway
GO:0030177 positive regulation of Wnt signaling pathway
GO:0060670 branching involved in labyrinthine layer morphogenesis
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:2000052 positive regulation of non-canonical Wnt signaling pathway
GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000884 Thrombospondin type-1 (TSP1) repeatRepeatRepeat
IPR006212 Furin-like repeatRepeatRepeat
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR036383 Thrombospondin type-1 (TSP1) repeat superfamilyFamilyHomologous superfamily
IPR042994 R-spondin-3FamilyFamily
IPR043601 R-spondin, Fu-CRD domainDomainDomain
IPR044004 Spondin-like TSP1 domainDomainDomain

Diseases

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