Entity Details

Primary name PGRP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75594
EntryNamePGRP1_HUMAN
FullNamePeptidoglycan recognition protein 1
TaxID9606
Evidenceevidence at protein level
Length196
SequenceStatuscomplete
DateCreated2001-10-18
DateModified2021-06-02

Ontological Relatives

GenesPGLYRP1

GO terms

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GOName
GO:0005576 extracellular region
GO:0008270 zinc ion binding
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity
GO:0009253 peptidoglycan catabolic process
GO:0016019 peptidoglycan immune receptor activity
GO:0016045 detection of bacterium
GO:0019730 antimicrobial humoral response
GO:0031640 killing of cells of other organism
GO:0035580 specific granule lumen
GO:0042834 peptidoglycan binding
GO:0043312 neutrophil degranulation
GO:0045087 innate immune response
GO:0050830 defense response to Gram-positive bacterium
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
GO:0070062 extracellular exosome
GO:0097013 phagocytic vesicle lumen
GO:1904724 tertiary granule lumen

Subcellular Location

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Subcellular Location
Cytoplasmic granule
Secreted

Domains

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DomainNameCategoryType
IPR002502 N-acetylmuramoyl-L-alanine amidase domainDomainDomain
IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteriaDomainDomain
IPR015510 Peptidoglycan recognition proteinFamilyFamily
IPR017331 Peptidoglycan recognition protein, PGRP-SFamilyFamily
IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
PGRP1_HUMANHPBP1_HUMANBioGRID21247889 details
PGRP1_HUMAN1433Z_HUMANMINT15161933 details