Entity Details

Primary name M3K6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95382
EntryNameM3K6_HUMAN
FullNameMitogen-activated protein kinase kinase kinase 6
TaxID9606
Evidenceevidence at protein level
Length1288
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesMAP3K6

GO terms

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GOName
GO:0000186 obsolete activation of MAPKK activity
GO:0000287 magnesium ion binding
GO:0004672 protein kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005524 ATP binding
GO:0006468 protein phosphorylation
GO:0007165 signal transduction
GO:0007257 obsolete activation of JUN kinase activity
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR013761 Sterile alpha motif/pointed domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR025136 MAP3K, TRAFs-binding domainDomainDomain
IPR043969 MAP3K, PH domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB12010 FostamatinibDrugbanksmall molecule