Entity Details

Primary name GRM7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14831
EntryNameGRM7_HUMAN
FullNameMetabotropic glutamate receptor 7
TaxID9606
Evidenceevidence at protein level
Length915
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesGRM7

GO terms

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GOName
GO:0001640 adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
GO:0001642 group III metabotropic glutamate receptor activity
GO:0005509 calcium ion binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005938 cell cortex
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007196 adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway
GO:0007216 G protein-coupled glutamate receptor signaling pathway
GO:0007268 chemical synaptic transmission
GO:0007605 sensory perception of sound
GO:0008066 glutamate receptor activity
GO:0010855 adenylate cyclase inhibitor activity
GO:0014050 negative regulation of glutamate secretion
GO:0016021 integral component of membrane
GO:0016595 glutamate binding
GO:0030165 PDZ domain binding
GO:0030424 axon
GO:0030425 dendrite
GO:0032279 asymmetric synapse
GO:0043198 dendritic shaft
GO:0043235 receptor complex
GO:0045211 postsynaptic membrane
GO:0048786 presynaptic active zone
GO:0051966 regulation of synaptic transmission, glutamatergic
GO:0070905 serine binding

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000162 GPCR, family 3, metabotropic glutamate receptorFamilyFamily
IPR000337 GPCR, family 3FamilyFamily
IPR001828 Receptor, ligand binding regionDomainDomain
IPR001883 GPCR, family 3, metabotropic glutamate receptor 7FamilyFamily
IPR011500 GPCR, family 3, nine cysteines domainDomainDomain
IPR017978 GPCR family 3, C-terminalDomainDomain
IPR017979 GPCR, family 3, conserved siteSiteConserved site
IPR028082 Periplasmic binding protein-like IFamilyHomologous superfamily
IPR038550 GPCR, family 3, nine cysteines domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00142 Glutamic acidDrugbanksmall molecule