Entity Details

Primary name C8B
Entity type gene
Source Source Link

Details

PrimaryID732
RefseqGeneNG_007285
SymbolC8B
Namecomplement C8 beta chain
Chromosome1
Location1p32.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1987-11-04
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCO8B_HUMAN

GO terms

Show/Hide Table
GOName
GO:0005576 extracellular region
GO:0005579 membrane attack complex
GO:0006955 immune response
GO:0006956 complement activation
GO:0006957 complement activation, alternative pathway
GO:0006958 complement activation, classical pathway
GO:0016020 membrane
GO:0019835 cytolysis
GO:0030449 regulation of complement activation
GO:0044877 protein-containing complex binding
GO:0070062 extracellular exosome
GO:1903561 extracellular vesicle

Diseases

Show/Hide Table
Disease IDSourceNameDescription
613789 OMIMComplement component 8 deficiency, 2 (C8D2)A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis. Disease susceptibility is associated with variants affecting the gene represented in this entry.

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
C8BC5BioGRID, HPRD, IntAct26841837 30552328 3624872 details
C8BCLUBioGRID, HPRD8345200 details
C8BC8AHPRD10387094 details