Entity Details

Primary name RIMS2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UQ26
EntryNameRIMS2_HUMAN
FullNameRegulating synaptic membrane exocytosis protein 2
TaxID9606
Evidenceevidence at protein level
Length1411
SequenceStatuscomplete
DateCreated2003-08-29
DateModified2021-06-02

Ontological Relatives

GenesRIMS2

GO terms

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GOName
GO:0006886 intracellular protein transport
GO:0010628 positive regulation of gene expression
GO:0017156 calcium-ion regulated exocytosis
GO:0017157 regulation of exocytosis
GO:0019933 cAMP-mediated signaling
GO:0030073 insulin secretion
GO:0030154 cell differentiation
GO:0031267 small GTPase binding
GO:0042391 regulation of membrane potential
GO:0042734 presynaptic membrane
GO:0042995 cell projection
GO:0044325 transmembrane transporter binding
GO:0046872 metal ion binding
GO:0048167 regulation of synaptic plasticity
GO:0048786 presynaptic active zone
GO:0048788 cytoskeleton of presynaptic active zone
GO:0048791 calcium ion-regulated exocytosis of neurotransmitter
GO:0050806 positive regulation of synaptic transmission
GO:0061669 spontaneous neurotransmitter secretion
GO:0070062 extracellular exosome
GO:0097151 positive regulation of inhibitory postsynaptic potential
GO:1903861 positive regulation of dendrite extension
GO:2000300 regulation of synaptic vesicle exocytosis
GO:2000463 positive regulation of excitatory postsynaptic potential

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR000008 C2 domainDomainDomain
IPR001478 PDZ domainDomainDomain
IPR010911 Rab-binding domainDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR017455 Zinc finger, FYVE-relatedDomainDomain
IPR030631 Regulating synaptic membrane exocytosis protein 2FamilyFamily
IPR035892 C2 domain superfamilyFamilyHomologous superfamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily
IPR039032 Rim-likeFamilyFamily
IPR041282 FYVE-type zinc fingerDomainDomain
IPR041489 PDZ domain 6DomainDomain

Diseases

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