Entity Details

Primary name NR2E1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y466
EntryNameNR2E1_HUMAN
FullNameNuclear receptor subfamily 2 group E member 1
TaxID9606
Evidenceevidence at protein level
Length385
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesNR2E1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001662 behavioral fear response
GO:0002118 aggressive behavior
GO:0003707 steroid hormone receptor activity
GO:0004879 nuclear receptor activity
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0007399 nervous system development
GO:0007601 visual perception
GO:0008270 zinc ion binding
GO:0021542 dentate gyrus development
GO:0021764 amygdala development
GO:0021772 olfactory bulb development
GO:0021819 layer formation in cerebral cortex
GO:0021872 forebrain generation of neurons
GO:0021895 cerebral cortex neuron differentiation
GO:0021960 anterior commissure morphogenesis
GO:0030154 cell differentiation
GO:0030198 extracellular matrix organization
GO:0035019 somatic stem cell population maintenance
GO:0035176 social behavior
GO:0042826 histone deacetylase binding
GO:0043066 negative regulation of apoptotic process
GO:0045165 cell fate commitment
GO:0045665 negative regulation of neuron differentiation
GO:0045766 positive regulation of angiogenesis
GO:0045787 positive regulation of cell cycle
GO:0048712 negative regulation of astrocyte differentiation
GO:0048814 regulation of dendrite morphogenesis
GO:0048856 anatomical structure development
GO:0060041 retina development in camera-type eye
GO:0060164 regulation of timing of neuron differentiation
GO:0060291 long-term synaptic potentiation
GO:0090049 regulation of cell migration involved in sprouting angiogenesis
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000178 negative regulation of neural precursor cell proliferation
GO:2000179 positive regulation of neural precursor cell proliferation
GO:2000648 positive regulation of stem cell proliferation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000536 Nuclear hormone receptor, ligand-binding domainDomainDomain
IPR001628 Zinc finger, nuclear hormone receptor-typeDomainDomain
IPR001723 Nuclear hormone receptorFamilyFamily
IPR013088 Zinc finger, NHR/GATA-typeFamilyHomologous superfamily
IPR035500 Nuclear hormone receptor-like domain superfamilyFamilyHomologous superfamily

Diseases

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