Entity Details

Primary name MOES_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP26038
EntryNameMOES_HUMAN
FullNameMoesin
TaxID9606
Evidenceevidence at protein level
Length577
SequenceStatuscomplete
DateCreated1992-05-01
DateModified2021-06-02

Ontological Relatives

GenesMSN

GO terms

Show/Hide Table
GOName
GO:0001771 immunological synapse formation
GO:0001931 uropod
GO:0003725 double-stranded RNA binding
GO:0003779 actin binding
GO:0005102 signaling receptor binding
GO:0005200 structural constituent of cytoskeleton
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005902 microvillus
GO:0005925 focal adhesion
GO:0007159 leukocyte cell-cell adhesion
GO:0008360 regulation of cell shape
GO:0008361 regulation of cell size
GO:0009986 cell surface
GO:0010628 positive regulation of gene expression
GO:0016032 viral process
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0022612 gland morphogenesis
GO:0022614 membrane to membrane docking
GO:0030175 filopodium
GO:0031143 pseudopodium
GO:0031528 microvillus membrane
GO:0031982 vesicle
GO:0035722 interleukin-12-mediated signaling pathway
GO:0042098 T cell proliferation
GO:0045177 apical part of cell
GO:0045198 establishment of epithelial cell apical/basal polarity
GO:0048471 perinuclear region of cytoplasm
GO:0050839 cell adhesion molecule binding
GO:0050900 leukocyte migration
GO:0061028 establishment of endothelial barrier
GO:0070062 extracellular exosome
GO:0070489 T cell aggregation
GO:0071394 cellular response to testosterone stimulus
GO:0071803 positive regulation of podosome assembly
GO:0071944 cell periphery
GO:0072562 blood microparticle
GO:0072678 T cell migration
GO:1902115 regulation of organelle assembly
GO:1902966 positive regulation of protein localization to early endosome
GO:1903364 positive regulation of cellular protein catabolic process
GO:2000401 regulation of lymphocyte migration
GO:2000643 positive regulation of early endosome to late endosome transport

Subcellular Location

Show/Hide Table
Subcellular Location
Apical cell membrane
Cell membrane
Cell projection
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR000299 FERM domainDomainDomain
IPR000798 Ezrin/radixin/moesin-likeFamilyFamily
IPR008954 Moesin tail domain superfamilyFamilyHomologous superfamily
IPR011174 Ezrin/radixin/moesinFamilyFamily
IPR011259 Ezrin/radixin/moesin, C-terminalDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR014352 FERM/acyl-CoA-binding protein superfamilyFamilyHomologous superfamily
IPR018979 FERM, N-terminalDomainDomain
IPR018980 FERM, C-terminal PH-like domainDomainDomain
IPR019747 FERM conserved siteSiteConserved site
IPR019748 FERM central domainDomainDomain
IPR019749 Band 4.1 domainDomainDomain
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR035963 FERM superfamily, second domainFamilyHomologous superfamily
IPR041789 ERM family, FERM domain C-lobeDomainDomain

Diseases

Show/Hide Table

Interactions

61 interactions

InteractorPartnerSourcesPublicationsLink
MOES_HUMANNHRF1_HUMANBioGRID, HPRD, IntAct15020681 9430655 details
MOES_HUMANCD11B_HUMANBioGRID, IntAct21988832 details
MOES_HUMANMYPC2_HUMANBioGRID, IntAct23414517 details
MOES_HUMANVCAM1_HUMANBioGRID, HPRD, IntAct12082081 19738201 22623428 23463506 7884872 details
MOES_HUMANLRRK2_HUMANBioGRID, IntAct20642453 22363216 22952686 23241358 24351927 24695735 24904275 25009464 26824392 27357661 31046837 details
MOES_HUMANCD44_HUMANBioGRID, Molecular Connections23855374 9472040 details
MOES_HUMANEZRI_HUMANBioGRID, HPRD, IntAct15659383 26496610 29568061 34079125 7579708 8248180 details
MOES_HUMANTERF1_HUMANbhf-ucl, BioGRID21044950 details
MOES_HUMANRBTN2_HUMANBioGRID, IntAct32296183 details
MOES_HUMANPCNA_HUMANUniProt26030842 details
MOES_HUMANERBB2_HUMANBioGRID, IntAct31980649 details
MOES_HUMANCRUM1_HUMANUniProt17920587 details
MOES_HUMANTSC1_HUMANBioGRID, HPRD12226091 details
MOES_HUMANICAM3_HUMANBioGRID, HPRD11784723 23463506 9298994 details
MOES_HUMANNCF1_HUMANBioGRID, HPRD10436021 11716484 details
MOES_HUMANNCF4_HUMANBioGRID, HPRD11716484 details
MOES_HUMANLYAM1_HUMANBioGRID, HPRD11706008 details
MOES_HUMANLEUK_HUMANBioGRID, HPRD9472040 9616160 details
MOES_HUMANICAM2_HUMANBioGRID, HPRD9472040 details
MOES_HUMANSELPL_HUMANBioGRID12115638 details
MOES_HUMANVPS11_HUMANBioGRID21148287 details
MOES_HUMANTRI15_HUMANBioGRID25450970 details
MOES_HUMANSMUF1_HUMANBioGRID20804422 details
MOES_HUMANHLAC_HUMANIntAct17353931 details
MOES_HUMANSYUG_HUMANIntAct17353931 details
MOES_HUMANELF3_HUMANIntAct17353931 details
MOES_HUMANIKKE_HUMANIntAct17353931 details
MOES_HUMANAAKB1_HUMANIntAct17353931 details
MOES_HUMANCDK2_HUMANBioGRID, IntAct17353931 21319273 details
MOES_HUMANTRAF6_HUMANIntAct17353931 details
MOES_HUMANKSYK_HUMANMINT12387735 details
MOES_HUMANBID_HUMANBioGRID15659383 details
MOES_HUMANTR10B_HUMANBioGRID15659383 details
MOES_HUMANFADD_HUMANBioGRID15659383 details
MOES_HUMANTNFL6_HUMANBioGRID15659383 details
MOES_HUMANMK08_HUMANBioGRID15659383 details
MOES_HUMANTNR6_HUMANBioGRID15659383 details
MOES_HUMANRHOA_HUMANBioGRID15659383 details
MOES_HUMANGDIR1_HUMANBioGRID15659383 26344197 details
MOES_HUMANCASPA_HUMANBioGRID15659383 details
MOES_HUMANCASP8_HUMANBioGRID15659383 details
MOES_HUMANTNR1A_HUMANBioGRID15659383 details
MOES_HUMANMOES_HUMANBioGRID, HPRD10847681 details
MOES_HUMANSPTN1_HUMANBioGRID11441066 details
MOES_HUMANMCP_HUMANBioGRID, HPRD12082081 7884872 details
MOES_HUMANISG15_HUMANBioGRID16009940 details
MOES_HUMANBRCA1_HUMANBioGRID21282464 details
MOES_HUMANICAM1_HUMANBioGRID, HPRD12082081 23463506 details
MOES_HUMANCD81_HUMANBioGRID23463506 details
MOES_HUMANIGSF8_HUMANBioGRID23463506 details
MOES_HUMANABCE1_HUMANBioGRID25659154 details
MOES_HUMANU2AF2_HUMANBioGRID26641092 details
MOES_HUMANPD1L1_HUMANBioGRID32941674 details
MOES_HUMANBAP31_HUMANHPRD12594175 details
MOES_HUMANL1CAM_HUMANHPRD12070130 details
MOES_HUMANKPCT_HUMANHPRD9516463 9856983 details
MOES_HUMANPLEC_HUMANHPRD11441066 details
MOES_HUMANROCK1_HUMANHPRD9516463 9856983 details
MOES_HUMANPPM1B_HUMANHPRD10480873 details
MOES_HUMANPPM1A_HUMANHPRD10480873 details
MOES_HUMANC1QR1_HUMANHPRD15819698 details