Entity Details

Primary name SOX10
Entity type gene
Source Source Link

Details

PrimaryID6663
RefseqGeneNG_007948
SymbolSOX10
NameSRY-box transcription factor 10
Chromosome22
Location22q13.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-09-20
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsSOX10_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001216 DNA-binding transcription activator activity
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001701 in utero embryonic development
GO:0001755 neural crest cell migration
GO:0002009 morphogenesis of an epithelium
GO:0002052 positive regulation of neuroblast proliferation
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0007399 nervous system development
GO:0007422 peripheral nervous system development
GO:0008134 transcription factor binding
GO:0009653 anatomical structure morphogenesis
GO:0010626 negative regulation of Schwann cell proliferation
GO:0010628 positive regulation of gene expression
GO:0014003 oligodendrocyte development
GO:0014015 positive regulation of gliogenesis
GO:0022010 central nervous system myelination
GO:0030318 melanocyte differentiation
GO:0031315 extrinsic component of mitochondrial outer membrane
GO:0031643 positive regulation of myelination
GO:0032808 lacrimal gland development
GO:0035690 cellular response to drug
GO:0042802 identical protein binding
GO:0043066 negative regulation of apoptotic process
GO:0045893 positive regulation of transcription, DNA-templated
GO:0048469 cell maturation
GO:0048484 enteric nervous system development
GO:0048546 digestive tract morphogenesis
GO:0048589 developmental growth
GO:0048709 oligodendrocyte differentiation
GO:0061138 morphogenesis of a branching epithelium
GO:0071393 cellular response to progesterone stimulus
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:1990837 sequence-specific double-stranded DNA binding
GO:1990841 promoter-specific chromatin binding

Diseases

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Interactions

46 interactions

InteractorPartnerSourcesPublicationsLink
SOX10UBE2IBioGRID, HPRD, MINT16494873 29295999 details
SOX10SUMO1HPRD, MINT16494873 details
SOX10POU3F2BioGRID, HPRD, IntAct11029584 details
SOX10SOX10HPRD, IntAct11029584 details
SOX10PAX3BioGRID, HPRD, IntAct10942418 11029584 12668617 details
SOX10NMIBioGRID, HPRD, IntAct16214168 details
SOX10EXOC5BioGRID, IntAct21988832 details
SOX10CDK6BioGRID, IntAct22094256 details
SOX10CRXBioGRID, IntAct32296183 details
SOX10HSF4BioGRID, IntAct32296183 details
SOX10MAGED1BioGRID, IntAct32296183 details
SOX10DAZAP2BioGRID, IntAct32296183 details
SOX10POU6F2BioGRID, IntAct32296183 details
SOX10PPIAIntAct32814053 details
SOX10PRKCAIntAct32814053 details
SOX10YWHAGIntAct32814053 details
SOX10SETDB1IntAct32814053 details
SOX10KAT5IntAct32814053 details
SOX10LMO3IntAct32814053 details
SOX10GSK3BBioGRID26461473 details
SOX10MAPK1BioGRID29295999 details
SOX10PAX6HPRD16582099 details
SOX10MEOX1HPRD16582099 details
SOX10HIVEP1HPRD16582099 details
SOX10DLX5HPRD16582099 details
SOX10HHEXHPRD16582099 details
SOX10ALX4HPRD16582099 details
SOX10HOXA3HPRD16582099 details
SOX10POU3F3HPRD16582099 details
SOX10UTF1HPRD16582099 details
SOX10PRRX1HPRD16582099 details
SOX10HOXC4HPRD16582099 details
SOX10PRRX2HPRD16582099 details
SOX10EPAS1BioGRID23275444 details
SOX10FBXW7BioGRID26461473 details
SOX10CHD7BioGRID26928066 details
SOX10TCF12HPRD16582099 details
SOX10OLIG2HPRD16582099 details
SOX10JUNHPRD16582099 details
SOX10CEBPAHPRD16582099 details
SOX10EGR2HPRD16582099 details
SOX10SP1HPRD16582099 details
SOX10POU5F1HPRD16582099 details
SOX10SUMO2HPRD16494873 details
SOX10SUMO3HPRD16494873 details
SOX10OTUB2BioGRID30662561 details