Entity Details

Primary name XDH
Entity type gene
Source Source Link

Details

PrimaryID7498
RefseqGeneNG_008871
SymbolXDH
Namexanthine dehydrogenase
Chromosome2
Location2p23.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsXDH_HUMAN

GO terms

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GOName
GO:0001933 negative regulation of protein phosphorylation
GO:0001937 negative regulation of endothelial cell proliferation
GO:0002250 adaptive immune response
GO:0004854 xanthine dehydrogenase activity
GO:0004855 xanthine oxidase activity
GO:0005506 iron ion binding
GO:0005615 extracellular space
GO:0005777 peroxisome
GO:0005829 cytosol
GO:0006148 inosine catabolic process
GO:0006154 adenosine catabolic process
GO:0006195 purine nucleotide catabolic process
GO:0006196 AMP catabolic process
GO:0006204 IMP catabolic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007595 lactation
GO:0009055 electron transfer activity
GO:0009115 xanthine catabolic process
GO:0010629 negative regulation of gene expression
GO:0016226 iron-sulfur cluster assembly
GO:0016491 oxidoreductase activity
GO:0016529 sarcoplasmic reticulum
GO:0042803 protein homodimerization activity
GO:0043546 molybdopterin cofactor binding
GO:0045602 negative regulation of endothelial cell differentiation
GO:0046038 GMP catabolic process
GO:0046055 dGMP catabolic process
GO:0050660 flavin adenine dinucleotide binding
GO:0051537 2 iron, 2 sulfur cluster binding
GO:0051898 negative regulation of protein kinase B signaling
GO:0070674 hypoxanthine dehydrogenase activity
GO:0070675 hypoxanthine oxidase activity
GO:0071949 FAD binding
GO:1900745 positive regulation of p38MAPK cascade
GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway
GO:2000379 positive regulation of reactive oxygen species metabolic process
GO:2001213 negative regulation of vasculogenesis

Diseases

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Interactions

8 interactions

InteractorPartnerSourcesPublicationsLink
XDHGRIP1BioGRID, IntAct32296183 details
XDHUSP15BioGRID31578733 details
XDHBTN1A1HPRD12456835 details
XDHMYCBioGRID, IntAct21150319 details
XDHCCDC110BioGRID, IntAct28514442 details
XDHKIF14BioGRID31586073 details
XDHKIF23BioGRID31586073 details
XDHUFL1BioGRID32807901 details