Entity Details

Primary name SPRY4
Entity type gene
Source Source Link

Details

PrimaryID81848
RefseqGeneNG_034148
SymbolSPRY4
Namesprouty RTK signaling antagonist 4
Chromosome5
Location5q31.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-04-06
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsSPY4_HUMAN

GO terms

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GOName
GO:0004860 protein kinase inhibitor activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005925 focal adhesion
GO:0032587 ruffle membrane
GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway
GO:0043407 negative regulation of MAP kinase activity
GO:0046580 negative regulation of Ras protein signal transduction
GO:0048513 animal organ development
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:1900025 negative regulation of substrate adhesion-dependent cell spreading

Diseases

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Interactions

83 interactions

InteractorPartnerSourcesPublicationsLink
SPRY4TESK1BioGRID, HPRD, IntAct12027893 17974561 details
SPRY4CBLBioGRID, MINT18273061 details
SPRY4ZDHHC17BioGRID, IntAct24705354 details
SPRY4TNS2BioGRID, IntAct25814554 details
SPRY4RIN3BioGRID, IntAct25814554 details
SPRY4HOXA1BioGRID, IntAct32296183 details
SPRY4KRTAP5-11BioGRID, IntAct32296183 details
SPRY4KLHL38BioGRID, IntAct32296183 details
SPRY4COL8A1BioGRID, IntAct32296183 details
SPRY4NUTF2BioGRID, IntAct32296183 details
SPRY4POU4F2BioGRID, IntAct32296183 details
SPRY4ADAM12BioGRID, IntAct32296183 details
SPRY4CREB5BioGRID, IntAct32296183 details
SPRY4FHL2BioGRID, IntAct32296183 details
SPRY4EFEMP2BioGRID, IntAct32296183 details
SPRY4OTX1BioGRID, IntAct32296183 details
SPRY4VENTXBioGRID, IntAct32296183 details
SPRY4CASP6IntAct32814053 details
SPRY4CCKIntAct32814053 details
SPRY4CHATIntAct32814053 details
SPRY4CRYAA2IntAct32814053 details
SPRY4CRYAAIntAct32814053 details
SPRY4CTSDIntAct32814053 details
SPRY4FGFR3IntAct32814053 details
SPRY4GRNIntAct32814053 details
SPRY4GSNIntAct32814053 details
SPRY4HSPB1IntAct32814053 details
SPRY4LAMP2BioGRID, IntAct32814053 34079125 details
SPRY4PRKNIntAct32814053 details
SPRY4PRPS1IntAct32814053 details
SPRY4KLK6IntAct32814053 details
SPRY4RANIntAct32814053 details
SPRY4TTRIntAct32814053 details
SPRY4WFS1IntAct32814053 details
SPRY4STIP1IntAct32814053 details
SPRY4KIF1BIntAct32814053 details
SPRY4RNF11IntAct32814053 details
SPRY4UBQLN1IntAct32814053 details
SPRY4PRPF40AIntAct32814053 details
SPRY4COQ8AIntAct32814053 details
SPRY4SPRED1IntAct32814053 details
SPRY4SPRY4HPRD12027893 details
SPRY4RAF1BioGRID, HPRD12717443 details
SPRY4SPRY2BioGRID15004239 details
SPRY4GRB2BioGRID16893902 details
SPRY4GARRE1BioGRID29395067 details
SPRY4TMEM17BioGRID, IntAct26638075 details
SPRY4PIP4K2BBioGRID, IntAct28514442 details
SPRY4ORMDL3BioGRID, IntAct28514442 details
SPRY4BET1BioGRID, IntAct29568061 details
SPRY4LAMP1BioGRID, IntAct29568061 34079125 details
SPRY4TGOLN2BioGRID, IntAct29568061 details
SPRY4HRASBioGRID30442766 30639242 details
SPRY4KRASBioGRID30194290 30442766 34079125 details
SPRY4NRASBioGRID30442766 30639242 details
SPRY4CA9BioGRID28692057 details
SPRY4ANKFY1BioGRID34079125 details
SPRY4AP2B1BioGRID34079125 details
SPRY4ARF6BioGRID34079125 details
SPRY4B3GAT1BioGRID34079125 details
SPRY4C11orf52BioGRID34079125 details
SPRY4CAV1BioGRID34079125 details
SPRY4CXADRBioGRID34079125 details
SPRY4EBAG9BioGRID34079125 details
SPRY4ELOVL5BioGRID34079125 details
SPRY4GJA1BioGRID34079125 details
SPRY4GJD3BioGRID34079125 details
SPRY4LAMP3BioGRID34079125 details
SPRY4LAMTOR1BioGRID34079125 details
SPRY4LMAN1BioGRID34079125 details
SPRY4MARCKSBioGRID34079125 details
SPRY4RAB11ABioGRID34079125 details
SPRY4RAB2ABioGRID34079125 details
SPRY4RAB35BioGRID34079125 details
SPRY4RAB3BBioGRID34079125 details
SPRY4RAB4ABioGRID34079125 details
SPRY4RAB5ABioGRID34079125 details
SPRY4RAB5CBioGRID34079125 details
SPRY4RAB9ABioGRID34079125 details
SPRY4RHOBBioGRID34079125 details
SPRY4STX6BioGRID34079125 details
SPRY4STX7BioGRID34079125 details
SPRY4ZFPL1BioGRID34079125 details