Entity Details

Primary name ALKB5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6P6C2
EntryNameALKB5_HUMAN
FullNameRNA demethylase ALKBH5
TaxID9606
Evidenceevidence at protein level
Length394
SequenceStatuscomplete
DateCreated2006-05-30
DateModified2021-06-02

Ontological Relatives

GenesALKBH5

GO terms

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GOName
GO:0001666 response to hypoxia
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0006307 DNA dealkylation involved in DNA repair
GO:0006397 mRNA processing
GO:0006406 mRNA export from nucleus
GO:0007283 spermatogenesis
GO:0016607 nuclear speck
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
GO:0030154 cell differentiation
GO:0035515 oxidative RNA demethylase activity
GO:0035553 oxidative single-stranded RNA demethylation
GO:0043488 regulation of mRNA stability
GO:0046872 metal ion binding
GO:1990931 RNA N6-methyladenosine dioxygenase activity

Subcellular Location

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Subcellular Location
Nucleus speckle

Domains

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DomainNameCategoryType
IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-likeDomainDomain
IPR032860 RNA demethylase ALKBH5FamilyFamily
IPR037151 Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ALKB5_HUMANCSK21_HUMANBioGRID, IntAct22113938 details
ALKB5_HUMANOGT1_HUMANBioGRID32994395 details