Entity Details

Primary name FIGLA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6QHK4
EntryNameFIGLA_HUMAN
FullNameFactor in the germline alpha
TaxID9606
Evidenceevidence at protein level
Length219
SequenceStatuscomplete
DateCreated2004-08-16
DateModified2021-06-02

Ontological Relatives

GenesFIGLA

GO terms

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GOName
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007275 multicellular organism development
GO:0008134 transcription factor binding
GO:0032502 developmental process
GO:0046983 protein dimerization activity
GO:0048599 oocyte development
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Disease IDSourceNameDescription
612310 OMIMPremature ovarian failure 6 (POF6)An ovarian disorder defined as the cessation of ovarian function under the age of 40 years. It is characterized by oligomenorrhea or amenorrhea, in the presence of elevated levels of serum gonadotropins and low estradiol. The disease is caused by variants affecting the gene represented in this entry.

Interactions

9 interactions