Entity Details

Primary name MRAP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96G30
EntryNameMRAP2_HUMAN
FullNameMelanocortin-2 receptor accessory protein 2
TaxID9606
Evidenceevidence at protein level
Length205
SequenceStatuscomplete
DateCreated2005-07-05
DateModified2021-06-02

Ontological Relatives

GenesMRAP2

GO terms

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GOName
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0006112 energy reserve metabolic process
GO:0007631 feeding behavior
GO:0016021 integral component of membrane
GO:0030545 signaling receptor regulator activity
GO:0031780 corticotropin hormone receptor binding
GO:0031781 type 3 melanocortin receptor binding
GO:0031782 type 4 melanocortin receptor binding
GO:0031783 type 5 melanocortin receptor binding
GO:0042802 identical protein binding
GO:0070996 type 1 melanocortin receptor binding
GO:0072659 protein localization to plasma membrane
GO:0097009 energy homeostasis
GO:0106070 regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0106071 positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0106072 negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:1903077 negative regulation of protein localization to plasma membrane

Subcellular Location

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Subcellular Location
Cell membrane
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR028111 Melanocortin-2 receptor accessory protein familyFamilyFamily

Diseases

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Disease IDSourceNameDescription
601665 OMIMObesity (OBESITY)A condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat. Disease susceptibility may be associated with variants affecting the gene represented in this entry.