Entity Details

Primary name GWL_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96GX5
EntryNameGWL_HUMAN
FullNameSerine/threonine-protein kinase greatwall
TaxID9606
Evidenceevidence at protein level
Length879
SequenceStatuscomplete
DateCreated2005-07-05
DateModified2021-06-02

Ontological Relatives

GenesMASTL

GO terms

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GOName
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000278 mitotic cell cycle
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0006974 cellular response to DNA damage stimulus
GO:0016301 kinase activity
GO:0018105 peptidyl-serine phosphorylation
GO:0032154 cleavage furrow
GO:0032515 negative regulation of phosphoprotein phosphatase activity
GO:0035556 intracellular signal transduction
GO:0051301 cell division
GO:0051721 protein phosphatase 2A binding
GO:0051726 regulation of cell cycle
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity

Subcellular Location

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Subcellular Location
Cleavage furrow
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR000961 AGC-kinase, C-terminalDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR037638 Serine/threonine-protein kinase greatwall, catalytic domainDomainDomain

Diseases

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Interactions

3 interactions