Entity Details

Primary name MSH4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15457
EntryNameMSH4_HUMAN
FullNameMutS protein homolog 4
TaxID9606
Evidenceevidence at protein level
Length936
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesMSH4

GO terms

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GOName
GO:0000710 meiotic mismatch repair
GO:0000712 resolution of meiotic recombination intermediates
GO:0000795 synaptonemal complex
GO:0001541 ovarian follicle development
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005713 recombination nodule
GO:0007129 homologous chromosome pairing at meiosis
GO:0007131 reciprocal meiotic recombination
GO:0007283 spermatogenesis
GO:0007292 female gamete generation
GO:0008094 ATPase, acting on DNA
GO:0030983 mismatched DNA binding

Subcellular Location

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Subcellular Location
Chromosome

Domains

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DomainNameCategoryType
IPR000432 DNA mismatch repair protein MutS, C-terminalDomainDomain
IPR007696 DNA mismatch repair protein MutS, coreDomainDomain
IPR007860 DNA mismatch repair protein MutS, connector domainDomainDomain
IPR007861 DNA mismatch repair protein MutS, clampDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036187 DNA mismatch repair protein MutS, core domain superfamilyFamilyHomologous superfamily
IPR036678 MutS, connector domain superfamilyFamilyHomologous superfamily

Diseases

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