Entity Details
| Primary name |
IL21R_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | Q9HBE5 |
| EntryName | IL21R_HUMAN |
| FullName | Interleukin-21 receptor |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 538 |
| SequenceStatus | complete |
| DateCreated | 2002-05-02 |
| DateModified | 2021-06-02 |
Subcellular Location
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| Subcellular Location |
| Membrane |
Domains
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| Domain | Name | Category | Type |
| IPR003531 | Short hematopoietin receptor, family 1, conserved site | Site | Conserved site |
| IPR003961 | Fibronectin type III | Domain | Domain |
| IPR013783 | Immunoglobulin-like fold | Family | Homologous superfamily |
| IPR036116 | Fibronectin type III superfamily | Family | Homologous superfamily |
Diseases
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| Disease ID | Source | Name | Description |
| 615207 | OMIM | Immunodeficiency 56 (IMD56) | An autosomal recessive primary immunodeficiency characterized by B- and T-cell defects and variable dysfunction of NK cells. Patients tend to have normal numbers of lymphocytes, but show defective class-switched B-cells, low IgG, defective antibody response, and defective T-cell responses to certain antigens. The disease is caused by variants affecting the gene represented in this entry. |
Interactions
4 interactions