Entity Details

Primary name PROD_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO43272
EntryNamePROD_HUMAN
FullNameProline dehydrogenase 1, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length600
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesPRODH

GO terms

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GOName
GO:0004657 proline dehydrogenase activity
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0006560 proline metabolic process
GO:0006562 proline catabolic process
GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0010133 proline catabolic process to glutamate
GO:0010942 positive regulation of cell death
GO:0019470 4-hydroxyproline catabolic process
GO:0043231 intracellular membrane-bounded organelle
GO:0071949 FAD binding

Subcellular Location

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Subcellular Location
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR002872 Proline dehydrogenase domainDomainDomain
IPR015659 Proline oxidase familyFamilyFamily
IPR029041 FAD-linked oxidoreductase-likeFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00172 ProlineDrugbanksmall molecule
DB06756 Glycine betaineDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink