Entity Details

Primary name DUS2L_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NX74
EntryNameDUS2L_HUMAN
FullNametRNA-dihydrouridine(20) synthase [NAD(P)+]-like
TaxID9606
Evidenceevidence at protein level
Length493
SequenceStatuscomplete
DateCreated2005-08-16
DateModified2021-06-02

Ontological Relatives

GenesDUS2

GO terms

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GOName
GO:0000049 tRNA binding
GO:0002943 tRNA dihydrouridine synthesis
GO:0003725 double-stranded RNA binding
GO:0004860 protein kinase inhibitor activity
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0010181 FMN binding
GO:0017150 tRNA dihydrouridine synthase activity
GO:0050660 flavin adenine dinucleotide binding
GO:0060548 negative regulation of cell death
GO:0070402 NADPH binding
GO:0102264 tRNA-dihydrouridine20 synthase activity

Subcellular Location

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Subcellular Location
Cytoplasm
Endoplasmic reticulum

Domains

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DomainNameCategoryType
IPR013785 Aldolase-type TIM barrelFamilyHomologous superfamily
IPR014720 Double-stranded RNA-binding domainDomainDomain
IPR018517 tRNA-dihydrouridine synthase, conserved siteSiteConserved site
IPR035587 DUS-like, FMN-binding domainDomainDomain
IPR044463 DUS2, double-stranded RNA binding domainDomainDomain

Diseases

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Interactions

4 interactions