Entity Details

Primary name SYNC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO43776
EntryNameSYNC_HUMAN
FullNameAsparagine--tRNA ligase, cytoplasmic
TaxID9606
Evidenceevidence at protein level
Length548
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesNARS1

GO terms

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GOName
GO:0003676 nucleic acid binding
GO:0004816 asparagine-tRNA ligase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006418 tRNA aminoacylation for protein translation
GO:0006421 asparaginyl-tRNA aminoacylation
GO:0016477 cell migration
GO:0031728 CCR3 chemokine receptor binding
GO:0046983 protein dimerization activity
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIbFamilyFamily
IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N)DomainDomain
IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-typeDomainDomain
IPR004522 Asparagine-tRNA ligaseFamilyFamily
IPR006195 Aminoacyl-tRNA synthetase, class IIDomainDomain
IPR012340 Nucleic acid-binding, OB-foldFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00174 AsparagineDrugbanksmall molecule

Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
SYNC_HUMANLSM1_HUMANBioGRID, HPRD, IntAct15231747 details
SYNC_HUMANATX1_HUMANBioGRID, HPRD, IntAct16713569 32814053 details
SYNC_HUMANHSPB2_HUMANbhf-ucl, BioGRID26465331 details
SYNC_HUMANSUMO2_HUMANBioGRID32786267 details
SYNC_HUMANIKKE_HUMANIntAct17353931 details