Entity Details

Primary name EAA4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP48664
EntryNameEAA4_HUMAN
FullNameExcitatory amino acid transporter 4
TaxID9606
Evidenceevidence at transcript level
Length564
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesSLC1A6

GO terms

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GOName
GO:0001504 neurotransmitter uptake
GO:0005314 high-affinity glutamate transmembrane transporter activity
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006811 ion transport
GO:0006836 neurotransmitter transport
GO:0007268 chemical synaptic transmission
GO:0015183 L-aspartate transmembrane transporter activity
GO:0015810 aspartate transmembrane transport
GO:0015813 L-glutamate transmembrane transport
GO:0016020 membrane
GO:0042391 regulation of membrane potential
GO:0045111 intermediate filament cytoskeleton
GO:0046872 metal ion binding
GO:0098712 L-glutamate import across plasma membrane
GO:0098796 membrane protein complex
GO:0098978 glutamatergic synapse
GO:0099056 integral component of presynaptic membrane

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001991 Sodium:dicarboxylate symporterFamilyFamily
IPR018107 Sodium:dicarboxylate symporter, conserved siteSiteConserved site
IPR036458 Sodium:dicarboxylate symporter superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00142 Glutamic acidDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
EAA4_HUMANARI2_HUMANBioGRID, HPRD, IntAct16169070 details
EAA4_HUMANARHGB_HUMANHPRD11242047 details