Entity Details

Primary name SRP54_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP61011
EntryNameSRP54_HUMAN
FullNameSignal recognition particle 54 kDa protein
TaxID9606
Evidenceevidence at protein level
Length504
SequenceStatuscomplete
DateCreated2004-04-26
DateModified2021-06-02

Ontological Relatives

GenesSRP54

GO terms

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GOName
GO:0003723 RNA binding
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005786 signal recognition particle, endoplasmic reticulum targeting
GO:0005829 cytosol
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation
GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition
GO:0008312 7S RNA binding
GO:0016607 nuclear speck
GO:0019003 GDP binding
GO:0030593 neutrophil chemotaxis
GO:0030851 granulocyte differentiation
GO:0030942 endoplasmic reticulum signal peptide binding
GO:0031017 exocrine pancreas development
GO:0043021 ribonucleoprotein complex binding
GO:0045047 protein targeting to ER

Subcellular Location

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Subcellular Location
Cytoplasm
Endoplasmic reticulum
Nucleus speckle

Domains

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DomainNameCategoryType
IPR000897 Signal recognition particle, SRP54 subunit, GTPase domainDomainDomain
IPR003593 AAA+ ATPase domainDomainDomain
IPR004125 Signal recognition particle, SRP54 subunit, M-domainDomainDomain
IPR006325 Signal recognition particle, SRP54 subunit, eukaryoticFamilyFamily
IPR013822 Signal recognition particle SRP54, helical bundleDomainDomain
IPR022941 Signal recognition particle, SRP54 subunitFamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036225 SRP/SRP receptor, N-terminalFamilyHomologous superfamily
IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamilyFamilyHomologous superfamily
IPR042101 Signal recognition particle SRP54, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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