Entity Details

Primary name PAPP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13219
EntryNamePAPP1_HUMAN
FullNamePappalysin-1
TaxID9606
Evidenceevidence at protein level
Length1627
SequenceStatuscomplete
DateCreated2001-09-26
DateModified2021-06-02

Ontological Relatives

GenesPAPPA

GO terms

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GOName
GO:0004222 metalloendopeptidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0007565 female pregnancy
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0032354 response to follicle-stimulating hormone
GO:0044267 cellular protein metabolic process
GO:0051384 response to glucocorticoid

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000436 Sushi/SCR/CCP domainDomainDomain
IPR000800 Notch domainDomainDomain
IPR006558 LamG-like jellyroll foldDomainDomain
IPR008754 Peptidase M43, pregnancy-associated plasma-ADomainDomain
IPR011936 Myxococcus cysteine-rich repeatRepeatRepeat
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR024079 Metallopeptidase, catalytic domain superfamilyFamilyHomologous superfamily
IPR030433 Pappalysin-1FamilyFamily
IPR035976 Sushi/SCR/CCP superfamilyFamilyHomologous superfamily
IPR043543 Pappalysin-1/2FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB12695 Phenethyl IsothiocyanateDrugbanksmall molecule