Entity Details

Primary name GLO2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ16775
EntryNameGLO2_HUMAN
FullNameHydroxyacylglutathione hydrolase, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length308
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesHAGH

GO terms

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GOName
GO:0004416 hydroxyacylglutathione hydrolase activity
GO:0005737 cytoplasm
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0006090 pyruvate metabolic process
GO:0006750 glutathione biosynthetic process
GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
GO:0046872 metal ion binding

Subcellular Location

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Subcellular Location
Cytoplasm
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR001279 Metallo-beta-lactamaseDomainDomain
IPR017782 Hydroxyacylglutathione hydrolaseFamilyFamily
IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domainDomainDomain
IPR035680 Hydroxyacylglutathione hydrolase, MBL domainDomainDomain
IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-likeFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00143 GlutathioneDrugbanksmall molecule
DB03889 S-(N-hydroxy-N-bromophenylcarbamoyl)glutathioneDrugbanksmall molecule