Entity Details

Primary name RICTR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6R327
EntryNameRICTR_HUMAN
FullNameRapamycin-insensitive companion of mTOR
TaxID9606
Evidenceevidence at protein level
Length1708
SequenceStatuscomplete
DateCreated2007-10-23
DateModified2021-06-02

Ontological Relatives

GenesRICTOR

GO terms

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GOName
GO:0001938 positive regulation of endothelial cell proliferation
GO:0005829 cytosol
GO:0009792 embryo development ending in birth or egg hatching
GO:0010468 regulation of gene expression
GO:0016032 viral process
GO:0018105 peptidyl-serine phosphorylation
GO:0019901 protein kinase binding
GO:0030838 positive regulation of actin filament polymerization
GO:0031532 actin cytoskeleton reorganization
GO:0031932 TORC2 complex
GO:0032008 positive regulation of TOR signaling
GO:0032148 activation of protein kinase B activity
GO:0032956 regulation of actin cytoskeleton organization
GO:0033135 regulation of peptidyl-serine phosphorylation
GO:0038203 TORC2 signaling
GO:0043022 ribosome binding
GO:0043087 regulation of GTPase activity
GO:0043539 protein serine/threonine kinase activator activity
GO:0050727 regulation of inflammatory response
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0051896 regulation of protein kinase B signaling
GO:0051897 positive regulation of protein kinase B signaling
GO:1901796 regulation of signal transduction by p53 class mediator
GO:2000114 regulation of establishment of cell polarity

Subcellular Location

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Domains

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DomainNameCategoryType
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR028267 Rapamycin-insensitive companion of mTOR, N-terminal domainDomainDomain
IPR028268 Pianissimo familyFamilyFamily
IPR029259 Rapamycin-insensitive companion of mTOR, phosphorylation-sitePTMPTM
IPR029451 Rapamycin-insensitive companion of mTOR, middle domainDomainDomain
IPR029452 Rapamycin-insensitive companion of mTOR, domain 5DomainDomain
IPR029453 Rapamycin-insensitive companion of mTOR, domain 4DomainDomain

Diseases

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Interactions

58 interactions

InteractorPartnerSourcesPublicationsLink
RICTR_HUMANMTOR_HUMANBioGRID, DIP, HPRD, IntAct, MINT15268862 15467718 15718470 16183647 16221682 16603397 16919458 16962653 17043309 17277771 17386266 17461779 17565979 18030348 18339839 18504440 18505677 18566586 18566587 18570873 19114562 19145465 19446321 19619545 19875983 20427287 20978191 21045808 21177249 21321085 21343617 21376236 21795849 22084251 22285861 22307628 22544753 22990118 23263282 23297343 23872070 23953116 24036451 24375676 25273559 25897075 27043084 29059166 30865892 31665642 details
RICTR_HUMANLST8_HUMANBioGRID, IntAct17461779 17565979 18030348 18505677 21376236 22084251 28489822 28514442 31665642 details
RICTR_HUMANPRR5L_HUMANBioGRID, IntAct17461779 18030348 18505677 21964062 details
RICTR_HUMANSIN1_HUMANBioGRID, IntAct, MINT16962653 17043309 17461779 18030348 18505677 18566586 18566587 18570873 19875983 20832730 21045808 21177249 21343617 21376236 22084251 31665642 details
RICTR_HUMANILK_HUMANBioGRID, IntAct18339839 details
RICTR_HUMANKPCA_HUMANBioGRID, MINT18566587 details
RICTR_HUMANAKT1_HUMANBioGRID, IntAct15718470 16603397 18566587 19402821 21177249 21339740 21343617 21795849 22337773 22990118 25241761 25273559 details
RICTR_HUMANKS6B1_HUMANBioGRID, IntAct15809305 25241761 25273559 details
RICTR_HUMANHSP74_HUMANBioGRID17461779 18505677 details
RICTR_HUMANSGK1_HUMANBioGRID20832730 details
RICTR_HUMANCUL1_HUMANBioGRID20832730 details
RICTR_HUMANGSK3B_HUMANBioGRID21343617 25897075 details
RICTR_HUMANIKKB_HUMANBioGRID23872070 details
RICTR_HUMANIKKA_HUMANBioGRID23872070 details
RICTR_HUMANSIR1_HUMANBioGRID22084251 26453307 details
RICTR_HUMANGSK3A_HUMANBioGRID25897075 details
RICTR_HUMANPLK1_HUMANBioGRID25714006 details
RICTR_HUMAN4EBP1_HUMANBioGRID18606717 details
RICTR_HUMAN1433S_HUMANMINT15778465 details
RICTR_HUMAN1433E_HUMANIntAct, MINT17461779 19935711 details
RICTR_HUMANPREX1_HUMANBioGRID, I2D, IntAct17565979 21339740 details
RICTR_HUMANRPTOR_HUMANBioGRID, IntAct19145465 19446321 details
RICTR_HUMAN1433Z_HUMANIntAct, MINT19720745 28514442 details
RICTR_HUMANRAB1A_HUMANIntAct25446900 details
RICTR_HUMANCPSM_HUMANBioGRID17461779 details
RICTR_HUMANCLH1_HUMANBioGRID17461779 details
RICTR_HUMANTBA1A_HUMANBioGRID17461779 details
RICTR_HUMANTBA1B_HUMANBioGRID17461779 details
RICTR_HUMANTIA1_HUMANBioGRID17461779 details
RICTR_HUMANRS3A_HUMANBioGRID17461779 details
RICTR_HUMANRL13_HUMANBioGRID17461779 details
RICTR_HUMANABHGA_HUMANBioGRID17461779 details
RICTR_HUMANEHMT2_HUMANBioGRID17461779 details
RICTR_HUMANDHX36_HUMANBioGRID17461779 details
RICTR_HUMANDHRS4_HUMANBioGRID17461779 details
RICTR_HUMANRBX1_HUMANBioGRID20832730 details
RICTR_HUMANRL23_HUMANBioGRID21045808 details
RICTR_HUMANRS5_HUMANBioGRID21045808 details
RICTR_HUMANUSP9X_HUMANBioGRID22544753 details
RICTR_HUMANFBXW7_HUMANBioGRID22285861 25897075 details
RICTR_HUMANPINK1_HUMANBioGRID21177249 details
RICTR_HUMANBRCA1_HUMANBioGRID22990118 details
RICTR_HUMANDDB1_HUMANBioGRID23297343 details
RICTR_HUMANPDIA3_HUMANBioGRID21321085 details
RICTR_HUMANFKBP8_HUMANBioGRID17991864 details
RICTR_HUMANGBB1_HUMANBioGRID24462769 details
RICTR_HUMANGBG2_HUMANBioGRID24462769 details
RICTR_HUMANPAR6A_HUMANBioGRID20978191 details
RICTR_HUMANNBN_HUMANBioGRID23762398 details
RICTR_HUMANAGR2_HUMANBioGRID30575818 details
RICTR_HUMANRASH_HUMANBioGRID30442766 30639242 details
RICTR_HUMANRASK_HUMANBioGRID30442766 30639242 34079125 details
RICTR_HUMANRASN_HUMANBioGRID30442766 30639242 details
RICTR_HUMANLANC2_HUMANBioGRID25273559 details
RICTR_HUMANMARCS_HUMANBioGRID30942445 34079125 details
RICTR_HUMANMUC18_HUMANBioGRID31665642 details
RICTR_HUMANUBR5_HUMANBioGRID32867711 details
RICTR_HUMANLNP_HUMANBioGRID32433973 details