Entity Details

Primary name TPTE2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6XPS3
EntryNameTPTE2_HUMAN
FullNamePhosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2
TaxID9606
Evidenceevidence at protein level
Length522
SequenceStatuscomplete
DateCreated2006-02-21
DateModified2021-06-02

Ontological Relatives

GenesTPTE2

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0004725 protein tyrosine phosphatase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006470 protein dephosphorylation
GO:0006661 phosphatidylinositol biosynthetic process
GO:0008285 negative regulation of cell population proliferation
GO:0014065 phosphatidylinositol 3-kinase signaling
GO:0016021 integral component of membrane
GO:0016311 dephosphorylation
GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
GO:0042995 cell projection
GO:0046856 phosphatidylinositol dephosphorylation
GO:0048870 cell motility
GO:0051896 regulation of protein kinase B signaling

Subcellular Location

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Subcellular Location
Cytoplasm
Endoplasmic reticulum membrane
Golgi apparatus membrane

Domains

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DomainNameCategoryType
IPR014020 Tensin phosphatase, C2 domainDomainDomain
IPR016130 Protein-tyrosine phosphatase, active siteSiteActive site
IPR027359 Voltage-dependent channel domain superfamilyFamilyHomologous superfamily
IPR029021 Protein-tyrosine phosphatase-likeFamilyHomologous superfamily
IPR029023 Tensin-type phosphatase domainDomainDomain

Diseases

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Interactions

5 interactions