Entity Details

Primary name MET16_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ86W50
EntryNameMET16_HUMAN
FullNameRNA N6-adenosine-methyltransferase METTL16
TaxID9606
Evidenceevidence at protein level
Length562
SequenceStatuscomplete
DateCreated2007-11-13
DateModified2021-06-02

Ontological Relatives

GenesMETTL16

GO terms

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GOName
GO:0001734 mRNA (N6-adenosine)-methyltransferase activity
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006402 mRNA catabolic process
GO:0006556 S-adenosylmethionine biosynthetic process
GO:0010608 posttranscriptional regulation of gene expression
GO:0030629 U6 snRNA 3'-end binding
GO:0035613 RNA stem-loop binding
GO:0048024 regulation of mRNA splicing, via spliceosome
GO:0052907 23S rRNA (adenine(1618)-N(6))-methyltransferase activity
GO:0061157 mRNA destabilization
GO:0070475 rRNA base methylation
GO:0080009 mRNA methylation
GO:0120048 U6 snRNA (adenine-(43)-N(6))-methyltransferase activity
GO:0120049 snRNA (adenine-N6)-methylation
GO:1905869 negative regulation of 3'-UTR-mediated mRNA stabilization

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR010286 METTL16/RlmF familyFamilyFamily
IPR017182 Methyltransferase METTL16/PsiMFamilyFamily
IPR029063 S-adenosyl-L-methionine-dependent methyltransferaseFamilyHomologous superfamily

Diseases

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Interactions

4 interactions