Entity Details

Primary name SKAP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ86WV1
EntryNameSKAP1_HUMAN
FullNameSrc kinase-associated phosphoprotein 1
TaxID9606
Evidenceevidence at protein level
Length359
SequenceStatuscomplete
DateCreated2007-01-09
DateModified2021-06-02

Ontological Relatives

GenesSKAP1

GO terms

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GOName
GO:0001772 immunological synapse
GO:0001954 positive regulation of cell-matrix adhesion
GO:0002250 adaptive immune response
GO:0002821 positive regulation of adaptive immune response
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0017124 SH3 domain binding
GO:0019901 protein kinase binding
GO:0019903 protein phosphatase binding
GO:0033625 positive regulation of integrin activation
GO:0033634 positive regulation of cell-cell adhesion mediated by integrin
GO:0034116 positive regulation of heterotypic cell-cell adhesion
GO:0042101 T cell receptor complex
GO:0042169 SH2 domain binding
GO:0044853 plasma membrane raft
GO:0044877 protein-containing complex binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0050852 T cell receptor signaling pathway
GO:0072659 protein localization to plasma membrane
GO:1903039 positive regulation of leukocyte cell-cell adhesion

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001452 SH3 domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR035765 Src kinase-associated phosphoprotein 1, SH3 domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR037781 SKAP familyFamilyFamily

Diseases

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