Entity Details

Primary name HDBP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IV16
EntryNameHDBP1_HUMAN
FullNameGlycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1
TaxID9606
Evidenceevidence at protein level
Length184
SequenceStatuscomplete
DateCreated2008-02-05
DateModified2021-06-02

Ontological Relatives

GenesGPIHBP1

GO terms

Show/Hide Table
GOName
GO:0001523 retinoid metabolic process
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0006886 intracellular protein transport
GO:0008289 lipid binding
GO:0009897 external side of plasma membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0017038 protein import
GO:0031225 anchored component of membrane
GO:0031362 anchored component of external side of plasma membrane
GO:0034371 chylomicron remodeling
GO:0034394 protein localization to cell surface
GO:0035473 lipase binding
GO:0035478 chylomicron binding
GO:0042632 cholesterol homeostasis
GO:0045056 transcytosis
GO:0050821 protein stabilization
GO:0051004 regulation of lipoprotein lipase activity
GO:0051006 positive regulation of lipoprotein lipase activity
GO:0070328 triglyceride homeostasis
GO:0071503 response to heparin
GO:0071813 lipoprotein particle binding
GO:0090321 positive regulation of chylomicron remnant clearance
GO:0140318 protein transporter activity

Subcellular Location

Show/Hide Table
Subcellular Location
Apical cell membrane
Basolateral cell membrane
Cell membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR016054 Ly-6 antigen/uPA receptor-likeDomainDomain

Diseases

Show/Hide Table
Disease IDSourceNameDescription
615947 OMIMHyperlipoproteinemia 1D (HLPP1D)An autosomal recessive disorder characterized by hyperlipoproteinemia, decreased plasma LPL levels in some patients, high plasma triglyceride levels, and refractory fasting chylomicronemia. The disease is caused by variants affecting the gene represented in this entry.

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
HDBP1_HUMANLIPL_HUMANbhf-ucl, UniProt20124439 30559189 details